Associations of DAT SPECT and TCS with prodromal features of Parkinson’s disease: results in PREDICT-PD participants
Objective: To examine whether changes on dopamine reuptake transporter (DAT) SPECT and transcranial sonography (TCS) correlated with Parkinson’s disease (PD) risk scores and other prodromal…Altered intrinsic brain functional connectivity in drug-naïve Parkinson’s disease with LRRK2 mutation
Objective: This study aimed to compare the alterations in the cortico-striatal functional connectivity (FC) of drug-naïve Parkinson’s disease (PD) patients with the leucine-rich repeat kinase…The Relative Preservation of the Dopaminergic Neuroal Loss of Patients with Parkinson’s Disease Having Dopamine-Unresponsive Resting Tremor
Objective: To investigate the difference of dopaminergic neuronal loss between PD patients with dopamine-unresponsive and -responsive resting tremor. Background: Resting tremor (RT) is one of…Link between striatal dopamine uptake and cortical dysconnectivity in Parkinson’s disease
Objective: This study aims to explore pathways of reduced striatal dopamine synthesis in PD that may affect striato-cortical connectivity and implicate in altered glucose metabolism…The combination of the MIBG myocardial scintigraphy and DATSPECT contributes to the diagnosis of PD and other related disorders.
Objective: To evaluate MIBG and DAT SPECT for the diagnosis of Parkinson’s disease (PD) and related disorders, we performed 123I-meta-iodobenzylguanzylguanidine (MIBG) myocardial scintigraphy and (123I)-FP-CIT…Longitudinal white matter microstructural change in Parkinson’s disease
Objective: To map regional differences in rates of change in diffusion tensor imaging (DTI)-based measures of brain white matter microstructural integrity between Parkinson (PD) patients and…Swallowing difficulties and Parkinson’s disease
Objective: To investigate whether swallowing difficulties are associated with presynaptic dopaminergic deficits, distinct clinical phenotypes, CSF biomarkers as well as whether they can predict motor…Speech difficulties are linked to striatal dopaminergic deficits and cognitive decline in early de novo patients with Parkinson’s disease
Objective: To investigate whether speech difficulties are associated with striatal dopaminergic deficits and whether are linked to progression of symptoms in early de novo patients…Resting state functional connectivity in PD patients with and without Freezing of gait
Objective: To investigate resting state functional connectivity (rsFC) abnormalities in patients with Parkinson's disease (PD), either with (PD-FOG) or without freezing of gait (PD no-FOG). …Longitudinal comparison of 11C-PE2I and 18F-DOPA PET for assessing severity and rate of disease progression in patients with Parkinson’s disease
Objective: To directly compare 18F-DOPA with a highly specific dopamine transporter radioligand 11C-PE2I, for the assessment of motor severity and rate of progression in Parkinson's…
