Comparison of four DBS lead designs under voltage and current operating modes based on patient specific simulations
Objective: To quantitatively compare the spatial extension of the electric field generated by four different lead designs operated under voltage and current modes. Background: Conventional…Electrophysiological activity of anatomically identified STN subterritories in Parkinson’s disease
Objective: To characterize the electrophysiological activity of the subthalamic nucleus (STN) functional subterritories, as anatomically defined on fused CT/MRI images or by the recording tract…Deep brain stimulation in the STN of a Parkinsonian rat model overexpressing human A53T α-synuclein in the substantia nigra – A proof of principle
Objective: To determine if subthalamic nucleus (STN)-deep brain stimulation (DBS) leads to a measurable functional improvement of motor deficits in an AAV1/2 A53T α-synuclein (aSyn)…Changes in mood and behavior following DBS – Measurement by self-reported questionaires
Objective: Behaviour can change following deep brain stimulation (DBS) in patients with movement disorders. Underlying mechanisms are different activation of the brain target, changes in…MR-guided high intensity focused ultrasound in Parkinson’s disease: A series of 5 cases
Objective: We present results of an ongoing trial of unilateral transcranial MR-guided high intensity focused ultrasound (tcMRgFUS) ablation of the pallido-thalamic tract (PTT, fasciculus thalamicus)…Comparison of effect of variable deep brain stimulation (DBS) frequencies on gait and balance in Parkinson’s disease (PD) patients with either bilateral GPi or STN stimulators employing wearable wireless sensors
Objective: To compare the effect of variable Deep brain Stimulation (DBS) frequencies on gait and balance in Parkinson's disease (PD) patients with either bilateral GPi…The effects of 60 Hz frequency of STN-DBS on gait in Parkinson’s disease
Objective: To evaluate the effect of low frequency (60Hz) deep brain stimulation of the subthalamic nucleus (STN-DBS) on gait in patients with Parkinson's disease (PD)…An investigation of Parkinson’s disease patients’ desired control over the DBS stimulator
Objective: To understand changes in patients' desired control of the DBS stimulator in a consecutive series of subjects who underwent DBS for the treatment of…Pisa syndrome in Parkinson’s disease effectively treated with subthalmic deep brain stimulation: Case report
Objective: To report the case of a 67-year-old Parkinsonian patient with significant and disabling Pisa syndrome (PS) successfully treated with subthalamic nucleus deep brain stimulation…Effect of bilateral subthalamic nuclei deep brain stimulation on impulse control disorders in PD
Objective: To study the effects of bilateral subthalamic nuclei stimulation on impulse control disorders(ICDs) in Parkinson's disease (PD). Background: Impulse control disorders(ICDs) cause significant morbidity…
