MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    Altered cerebello-thalamo-cortical pathway in Huntington’s disease

    J.F. Martín-Rodríguez, M. Gómez-Crespo, M.T. Cáceres-Redondo, L. Vargas-González, F.J. Palomar, P. Porcacchia, P. Álvarez de Toledo, J.M. Oropesa-Ruiz, F. Carrillo, I. Huertas-Fernández, S. Jesús, P. Mir (Seville, Spain)

    Objective: This study aims to assess the functional integrity of the cerebello-thalamo-cortical (CTC) pathway in patients with Huntington's disease (HD) through transcranial magnetic stimulation (TMS).…
  • 2016 International Congress

    Structural connectivity networks in prodromal and clinical Huntington’s disease

    C. Sanchez-Castañeda, H. Baggio, U. Sabatini, F. Squitieri, C. Junque (Barcelona, Spain)

    Objective: To investigate how structural connectivity correlates with the number of CAG repeats, disease evolution and clinical measures in presymptomatic (preHD) and clinical Huntington Disease…
  • 2016 International Congress

    Indirect comparison of tolerability of deutetrabenazine and tetrabenazine in the FIRST-HD and TETRA-HD trials

    D.O. Claassen, B. Carroll, L.M. De Boer, E. Wu, R. Ayyagari, S. Gandhi, D. Stamler (Nashville, TN, USA)

    Objective: To compare the tolerability of deutetrabenazine (DTB) and tetrabenazine (TBZ) as observed in the FIRST-HD (NCT01795859) and TETRA-HD (NCT00219804) trials for the treatment of…
  • 2016 International Congress

    Temporal course of the UHDRS chorea score in Huntington disease

    T.J. Felong, P. Auinger, S. Gandhi, V. Abler, K. Biglan, S. Papapetropoulos, C. Venuto, R. Dorsey (Rochester, NY, USA)

    Objective: To describe the temporal course of Huntington disease (HD) chorea using the total maximal chorea score of the Unified Huntington Disease Rating Scale -…
  • 2016 International Congress

    Temporal course of the total motor score in Huntington disease

    P. Auinger, T.J. Felong, S. Gandhi, V. Abler, K. Biglan, S. Papapetropoulos, C. Venuto, R. Dorsey (Rochester, NY, USA)

    Objective: To describe the temporal course of motor features in Huntington disease (HD) using the Unified Huntington Disease Rating Scale - Total Motor Score (UHDRS-TMS)…
  • 2016 International Congress

    Clinical presentation and genetic characteristics of Huntingtons disease in Croatia: Thirty years of experience

    M. Relja, I. Jurjevic, K. Blazina, V. Miletic, N. Klepac (Zagreb, Croatia)

    Objective: To report our experience over 30 years with patients with Huntington's disease disease (HD) in Croatia and to assess the presence of oxidative stress…
  • 2016 International Congress

    Demographic and phenotypic comparison of Huntington’s disease in Europe and North America: Data from REGISTRY and COHORT, two prospective observational cohort studies

    M. Orth, J. Bronzova, C. Tritsch, R. Dorsay, J.M. Burgunder, A. Gemperli (Ulm, Germany)

    Objective: We tested the assumption that the demographic and clinical spectrum of Huntington's disease (HD) is fairly similar irrespective of the geographical region of origin…
  • 2016 International Congress

    Maintenance of balance function in patients with HD treated with deutetrabenazine, as measured by Berg balance test (BBT) in First-HD

    D.O. Claassen, D. Oakes, D. Stamler, V. Sung, C.M. Testa, S. Frank, On behalf of the First-HD HSG Investigators (Nashville, TN, USA)

    Objective: To assess the effect of deutetrabenazine treatment on balance using the BBT in patients with HD in First-HD. Background: Patients with HD have disrupted…
  • 2016 International Congress

    Fifteen years of clinical trials in Huntington’s disease: Too many clinical trial failures

    A.M. Travessa, F.B. Rodrigues, T.A. Mestre, C. Sampaio, J.J. Ferreira (Lisboa, Portugal)

    Objective: To investigate the trends in Huntington's disease (HD) therapeutic development by analyzing interventional clinical trials publicly registered for the last 15 years. Background: Like…
  • 2016 International Congress

    Fast and simple non-invasive screening tool for mitochondrial changes in Huntington’s disease

    P. Dušek, M. Rodinová, I. Lišková, E. Trefilová, Z. Ellederová, J. Klempír, J. Roth, H. Hansíková (Prague, Czech Republic)

    Objective: To use Complex I and Complex IV Human Protein Quantity Dipstick Assay Kits to analyse mitochondrial changes in buccal epithelial cells of patients with…
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