Dopamine reduces Parkinson’s tremor through increased thalamic inhibition
Objective: To identify cerebral mechanisms explaining the effects of dopamine on rest tremor in Parkinson's disease. Background: Resting tremor in Parkinson's disease is related to…Neuromelanin in Parkinson’s disease: A 3 T MRI study
Objective: The purpose of this study was to investigate whether the signal intensity of the substantia nigra pars compacta (SNc) and locus coeruleus (LC) on…Nigrostriatal degeneration and serum BDNF levels in patients with “de novo” untreated Parkinson’s disease
Objective: To evaluate serum Brain-Derived NeurotrophicFactor(BDNF) levels in “de novo” untreated Parkinson's disease (PD) patients and their relationship to nigrostriatal degeneration measured with [123I]FP-CIT SPECT.…Neural mechanisms underlying step initiation failure in patients with Parkinson’s disease and freezing of gait
Objective: To investigate the neural mechanisms underlying gait initiation failure in Parkinson's disease patients with Freezing of Gait. Background: Freezing of Gait (FOG) is a…Progressive atrophy of parahippocampal gyrus correlates with Hoehn & Yahr stages of Parkinson’s disease: A voxel based morphometric study
Objective: To determine the gray matter (GM) changes in different clinical stages of Parkinson's disease (PD) using Voxel Based Morphometry (VBM). Background: PD is a…Brain iron levels in Parkinson’s disease by postmortem and MRI measurements: A systematic review and meta-analysis
Objective: In this study we performed a systematic review and meta-analysis aiming to understand PD-associated iron variations in all brain regions that have been examined,…Impaired cerebellum to motor cortex associative plasticity in Parkinson’s disease
Objective: To compare the corticocortical paired associative stimulation (PAS)-induced spike-timing dependent plasticity (STDP)-like plasticity between Parkinson's disease (PD) and healthy elder subjects. Background: Patients with…Botulinum toxin treatment of freezing of gait in Parkinson’s disease patients as reflected in functional magnetic resonance imaging of leg movement
Objective: To reflect botulinum toxin treatment of freezing of gait in Parkinson´s disease patients in functional magnetic resonance imaging of leg movement. Background: Freezing of…Freezing of gait in Parkinson’s disease: A stopping deficit?
Objective: We evaluated the role of inhibition in freezing of gait, and related performance on a behavioral stopping task to the structural integrity of the…Parkinson’s disease-linked mutation in DNAJC13 causes specific trafficking defect in endosomal pathway
Objective: The aim of this study is to investigate the effect of mutant DNAJC13 on the vesicle transport machinery using cultured cellular model. Background: Recently,…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.