Expanding the Phenotypic Spectrum of PRRT2 Channelopathy: A Homozygous Mutation With Early Epilepsy, Autism And Dysmorphism In A Consanguineous Family
Objective: Case Report Background: A child born to third-degree consanguineous parents presented with seizures beginning at 2.5 months of age. Over time, the child developed…Choroid Plexus Morphology and Enhancement as Imaging Markers for Early Differentiation of Multiple System Atrophy and Parkinson’s Disease
Objective: To characterize choroid plexus (ChP) morphology and enhancement in multiple system atrophy (MSA) and Parkinson’s disease (PD), investigate their associations with ventricular morphology and…Comparison of Regional Perfusion Patterns in Clinical Subtypes of PSP and CBD: Dual Phase [¹⁸F]FP CIT PET Study
Objective: To investigate the regional perfusion patterns using PET imaging across various clinical subtypes of PSP and CBD. Background: On MRI, PSP typically shows midbrain…Engage in Healthy Eating: A Community-Guided Approach to Culturally Sensitive Nutrition Support for People with Parkinson’s Disease (PD)
Objective: To co-develop a culturally affirming, family-centered Healthy Eating Program with community members for managing PD symptoms and achieving personal wellness goals. Background: Growing evidence…Ipsilateral chorea due to thalamic hemorrhage: insights into network mechanisms of post-stroke hyperkinetic disorders
Objective: To report a case of ipsilateral chorea secondary to thalamic hemorrhage and discuss neurophysiological mechanisms of hyperkinetic movement disorders Background: Cerebrovascular disease accounts for…When Motion Ceases Twice: Delayed Post-Hypoxic Leukoencephalopathy with Parkinsonism, a Case Report.
Objective: To describe a challenging clinical case of akinetic-rigid syndrome in the setting of delayed post-hypoxic leukoencephalopathy (DPHL). Background: The susceptibility of basal ganglia to hypoxic-ischemic injury can lead to immediate…Clinical and Genetic Characteristics of SACS-Related Ataxia: A Case Series of 13 Patients from a Consanguineous Arab Population
Objective: To describe the clinical and genetic characteristics of patients with SACS-related ataxia in an Arab population. Background: Pathogenic variants in the SACS gene cause…Muscarinic receptor antagonism beyond M4 is required for efficacy in a preclinical model of dystonia and Parkinson’s disease
Objective: To inform the target activity profile of future movement disorder therapies, pre-clinical studies quantified the contribution of M4 receptor occupancy (M4RO) to reversal of…Intranasal Delivery of Berberine-Loaded Solid Lipid Nanoparticles Ameliorates Neuropathological and Behavioral Deficits in a Preclinical Alzheimer’s Model
Objective: To evaluate the pharmacokinetic profile and neuroprotective efficacy of intranasally administered berberine-loaded solid lipid nanoparticles (BE-SLN) in a streptozotocin (STZ)-induced rat model of Alzheimer’s…The “Guarda” (Tower) Drawing Test: A Novel Bedside Tool to Quantify Bradykinesia in Parkinson’s Disease
Objective: Quantify Bradykinesia Through Standardized Drawing in PD patients. Background: Bradykinesia is the cardinal symptom in Parkinson's Disease (PD). The slowing and progressive reduction in…
- « Previous Page
- 1
- …
- 191
- 192
- 193
- 194
- 195
- …
- 1942
- Next Page »