Normative Data for the IDEA Dementia Screen in Healthy Older Adults and People with Parkinson’s Disease in Ethiopia: A Comparative Cross Sectional Study
Objective: This study aims to establish Ethiopian normative data for IDEA in healthy older adults and People with Parkinson's disease, and to evaluate its appropriateness…Levodopa-Carbidopa Intestinal Gel Infusion Therapy in Advanced Parkinson’s Disease: Extension Study of Long-term outcomes of Single Centre experience
Objective: evaluate the long-term outcomes of levodopa-carbidopa intestinal gel (LCIG) infusion in patients with advanced PD with motor fluctuation in one centre Background: Levodopa-carbidopa intestinal…Scaling Evidence-based Community Rehabilitation for Parkinson’s disease for Singapore: A Nationwide RE-AIM Implementation Study Protocol
Objective: This study aims to evaluate the nationwide scale-up of standardized Parkinson’s rehabilitation programs across Singapore’s community care sector using the RE-AIM (Reach, Effectiveness, Adoption,…Genetic Architecture Of Intracranial Brain Calcification: A Systematic Review
Objective: To systematically identify monogenic disorders associated with intracranial intraparenchymal brain calcification and synthesise their clinical, radiological and molecular features. Background: Brain calcification is a…The “Guarda” (Tower) Drawing Test: A Novel Bedside Tool to Quantify Bradykinesia in Parkinson’s Disease
Objective: Quantify Bradykinesia Through Standardized Drawing in PD patients. Background: Bradykinesia is the cardinal symptom in Parkinson's Disease (PD). The slowing and progressive reduction in…Genome-wide Discovery of Genetic Modifiers of LRRK2 risk in Parkinson’s Disease Carriers across European Populations
Objective: To identify genetic risk modifiers for LRRK2 variant carriers of European ancestry. Background: The LRRK2 p.G2019S variant is associated with substantially elevated risk for…Non-Motor Symptom Burden as a Key Determinant of Disease Clustering in Parkinson’s Disease
Objective: To evaluate how non-motor symptoms drive the classification of Parkinson’s disease (PD) patients beyond standard motor subtyping. Background: While motor symptoms are the hallmark…Olfactory Groove Meningioma Presenting with Recurrent Falls and Dystonic Head Tremor An Unusual Clinical Presentation
Objective: To describe a rare presentation of olfactory groove meningioma. Background: Olfactory groove meningioma is a benign intracranial tumor arising from the dura of the…Targeted Repeat-Expansion Screening Highlights Unmet Genomic Needs in Genetically Naive Ataxia: A Ukrainian Single-Centre Pilot Study
Objective: To assess the diagnostic yield of targeted repeat-expansion testing in patients with genetically naïve ataxia after exclusion of secondary causes. Background: Progressive ataxia is…Sleep dysfunction and its clinical and video-polysomnographic correlates in patients with early Parkinson’s disease in comparison with early Progressive supranuclear palsy
Objective: To estimate the prevalence and characterise the extend of sleep dysfunction in early Progressive Supranuclear Palsy and in early Parkinson’s disease among the Indian…
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