MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    Risk factors for central nervous system side effects of amantadine

    M. Nagai, N. Miyaue, Y. Ito, Y. Yamanishi, R. Ando, Y. Ihara (Ehime, Japan)

    Objective: The purpose of this study was to investigate the threshold blood level of amantadine and risk factors for central nervous system (CNS) side effects…
  • 2025 International Congress

    Repetitive Transcranial Magnetic Stimulation For Freezing Of Gait And Motor Function In Parkinson’s Disease: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials

    J. Pitton Rissardo, A. Fornari Caprara (Camden, USA)

    Objective: To evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on motor function, freezing of gait (FOG), and mobility in patients with Parkinson’s disease…
  • 2025 International Congress

    Trihexyphenidyl as a Treatment for Severe Freezing of Gait in Parkinson’s Disease: A Case Report

    J. Ha, M. Ferris (Palo Alto, USA)

    Objective: To present a unique case in which trihexyphenidyl was used as an effective treatment to dramatically reduce freezing of gait (FoG) in a Parkinson’s…
  • 2025 International Congress

    Three-Year Single-Center Experience with Levodopa–Entacapone–Carbidopa Intestinal Gel in Advanced Parkinson’s Disease

    J. Szász, V. Constantin, K. Orbán-Kis, S. Bataga, R. Neagoe, M. Ciorba, K. Kelemen, I. Mihály, S. Szatmári (TARGU MURES, Romania)

    Objective: To evaluate the efficacy of Levodopa-Entacapone-Carbidopa Intestinal Gel (LECIG) in advanced Parkinson’s Disease (APD). Background: LECIG infusion has been available in Romania since 2021.…
  • 2025 International Congress

    Neural Mechanisms of Intermittent Theta Burst Stimulation for Depressive Symptoms in Parkinson’s Disease: Insights from fNIRS-Based Cortical Activation and Connectivity Dynamics

    Y. Zhang, M. Hou, Z. Liu (Shanghai, China)

    Objective: This study investigated the neural mechanisms underlying the effects of intermittent theta burst stimulation (iTBS) on depressive symptoms in Parkinson’s disease (PD-D) using functional…
  • 2025 International Congress

    Effect of Continuous Subcutaneous Infusion of Foslevodopa/Foscarbidopa on motor fluctuations, dyskinesia, and sleep; subjective vs. PKG watch recordings.

    M. Bradley, E. Donlon, A. Gallagher, C. O'Keefe, J. Inocentes, F. Ruggieri, R. Reilly, R. Walsh, T. Lynch, C. Fearon (Dublin, Ireland)

    Objective: To evaluate the impact of continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa on bradykinesia, dyskinesia, and sleep quality using self-reported Hauser diaries and Parkinson’s KinetiGraph…
  • 2025 International Congress

    Long-term effects of a periodic intensive rehabilitation program in People with Parkinson’s Disease

    Y. Yamaguchi, J. Ogawa, K. Kakegawa, M. Matsuda (Ginza, Chuo-ku, Japan)

    Objective: This study aimed to examine the long-term effects of a periodic intensive rehabilitation program incorporating tele-tools on the progression of motor symptoms in people…
  • 2025 International Congress

    Opicapone for OFF Motor Fluctuations in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Trials

    A. Fornari Caprara, J. Pitton Rissardo (Camden, USA)

    Objective: To evaluate the efficacy of opicapone 50 mg in reducing OFF time and improving motor function in Parkinson’s disease (PD) patients with motor fluctuations.…
  • 2025 International Congress

    Quercetin Reduces mtDNA Release in PRKN-Deficient and Oxidatively Stressed SH-SY5Y Cells

    G. Agyeah, J. Ghelfi, L. Gallucci, K. Wasner, P. Antony, A. Rakovic, S. Pereira, A. Grünewald (Belval Esch-sur-Alzette, Luxembourg)

    Objective: This study investigates the role of Parkin deficiency in mitochondrial dysfunction and its contribution to mitochondrial DNA (mtDNA) release in Parkinson’s disease (PD). We…
  • 2025 International Congress

    Does the cerebellum compensate to enable motor learning in Parkinson’s Disease?

    PC. Iyer, BE. Fisher (Los Angeles, USA)

    Objective: To test the causal relation between cerebellar function and learning in PD. Background: Neuroimaging studies reveal that people with Parkinson’s disease (PwPD) exhibit increased…
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