Unlocking Movement Disorder Specialist Capacity and Mitigating Risk: a Platform Solution for Cost Reduction and Care Optimization in Parkinson’s Disease
Objective: Improve patient and physician care delivery experience through a technology-driven coaching and triage system. Background: Limited worldwide supply of Parkinson’s specialty care restricts access…Deep Brain Stimulation Surgery – Hurdles and Maladies!
Objective: To describe the obstacles to Deep Brain Stimulation (DBS) surgery and analyse the surgical and hardware complications following DBS, the study reports on 25…The 2-Minute Walking Test Predicts Aerobic Fitness, Motor Function, and Brain Health in Parkinson’s Disease
Objective: To determine the association of performance on the 2-Minute Walking Test (2MWT) with aerobic fitness, motor and cognitive function, and brain health in mild…Slow-SPEED-NL: study protocol for a remote trial of exercise for Parkinson’s disease prevention
Objective: To determine the feasibility and preliminary efficacy of a remote exercise intervention in prodromal Parkinson’s disease (PD). Background: Disease-slowing interventions have been ineffective in…Incobotulinumtoxin A to Treat Sialorrhea in Parkinson’s Disease: a Real-life Study: 5-year Interim Results
Objective: We evaluate the long-term efficacy and safety of incobotulinumtoxinA injections in advanced Parkinson’s disease (PD) patients suffering from sialorrhea (10 injection cycles (IC)). Background:…Movement Disorders Associated with Infectious Encephalitis in Pediatric Patients
Objective: The objective of our study is to report the clinical and imaging profile of a cohort of pediatric patients with movement disorders (MDs) associated…A Head-Turning Case of SCA10 with Dystonia
Objective: Present a SCA10 patient presenting with rare phenomenology of dystonia in addition to ataxia. Background: The spinocerebellar ataxias (SCAs) are a heterogenous group of…Application of Neurophysiology in the Clinical Evaluation of Pediatric and Adolescent Patients with Tremor
Objective: We explored the utility of noninvasive electrophysiological tremor studies in patients referred for evaluation by pediatric movement specialists following their clinical assessment . The…Remotely-deployed gamification intervention to increase physical activity in Parkinson’s Disease
Objective: To describe a remote, behavioral intervention designed to increase daily steps in Veterans with PD and report interim results from an ongoing clinical trial…First-In-Human Single and Multiple Ascending Dose Trial Design of LY3962681, a Novel Intrathecally Delivered siRNA Targeting α-synuclein mRNA for the Treatment of Patients with Parkinson’s Disease
Objective: Development of a Phase 1 clinical trial evaluating LY3962681, a novel, intrathecally delivered siRNA directly targeting α-synucleinmRNA (SNCA) to reduce α-synuclein protein (ASYN), for the treatment of…
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