Somnolence-Related Events Over Time with Valbenazine Treatment for Chorea Associated with Huntington’s Disease
Objective: To present somnolence-related events over time from 2 studies of once-daily valbenazine, which is approved for chorea in adults with Huntington’s disease: KINECT®-HD (K-HD,…Application of Neurophysiology in the Clinical Evaluation of Pediatric and Adolescent Patients with Tremor
Objective: We explored the utility of noninvasive electrophysiological tremor studies in patients referred for evaluation by pediatric movement specialists following their clinical assessment . The…Daily-life Sensor Based Measurement of Tremor Presence and Amplitude
Objective: To evaluate the association between conventional clinical ratings of tremor and one week sensor-based monitoring of tremor in patients with Parkinson’s disease (PwPD). Background:…Exploring the non-invasive epigenetic screening test for hereditary dystonia DYT-KMT2B
Objective: To explore the altered H3K4me3 levels in non-neural tissue of DYT-KMT2B patients. Background: DYT-KMT2B, also known as DYT28, is a childhood-onset hereditary dystonia caused…Changes In Glucose Metabolism In Essential Tremor: Within And Beyond The Cerebello-Thalamo-Cortical Circuit
Objective: To investigate differences in brain glucose metabolism between patients with essential tremor and healthy controls using [18F]FDG PET brain imaging. Background: The pathophysiological mechanisms…Peri-Electrode Edema after Deep Brain Stimulation Implantation – Case Report and Literature Review
Objective: To report a case of peri-electrode edema after Deep Brain Stimulation (DBS), and discuss its main aspects. Background: PD is a neurodegenerative condition, and…Movement Disorders Associated with Infectious Encephalitis in Pediatric Patients
Objective: The objective of our study is to report the clinical and imaging profile of a cohort of pediatric patients with movement disorders (MDs) associated…Dysfluent Writing Behavior Associates with Reduced Striatal-cerebellar Connectivity in Writer’s Cramp Dystonia
Objective: The primary objective of this study was to identify the brain regions contributing to dysfluent writing behavior in a subtype of dystonia called writer’s…Repurposing Anti-Gout Medications for the Treatment of Parkinson’s Disease
Objective: To undertake a repurposing drug screen for Parkinson’s disease (PD) and further investigate the mechanism of action of top hits. To assess, in vivo,…Metabolic Regulators of Mitochondrial DNA Release in Cellular Models of PRKN-linked Parkinson’s Disease
Objective: Explore metabolic modulation as a disease-modifying target for inflammation in PRKN-PD Background: The release of mitochondrial DNA (mtDNA) is a well-documented phenotype in PRKN-linked…
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