Three-Year Single-Center Experience with Levodopa–Entacapone–Carbidopa Intestinal Gel in Advanced Parkinson’s Disease
Objective: To evaluate the efficacy of Levodopa-Entacapone-Carbidopa Intestinal Gel (LECIG) in advanced Parkinson’s Disease (APD). Background: LECIG infusion has been available in Romania since 2021.…Down-titration of levodopa complicated by catatonia
Objective: Provide evidence that reductions in levodopa can trigger catatonia Background: Dopamine dysregulation syndrome (DDS) occurs when patients crave and self-up-titrate levodopa, often leading to…Combining Machine Learning and Linear Mixed Models to Estimate Medication Effect in People with Parkinson’s Disease
Objective: To estimate medication effect, as the score difference between MDS-UPDRS III in OFF and ON-state, using a minimal set of clinical features. Background: The…Treatment with Mucuna pruriens Plus Solo Carbidopa Prescription in Patient Reluctant to Initiation of Traditional Levodopa/Carbidopa Medication
Objective: To see if treatment with Mucuna pruriens 2 capsules (15% levodopa) TID, plus solo carbidopa prescription 25mg TID in patient reluctant to traditional levodopa/carbidopa management could help…Efficacy of LSVT-BIG Treatment Compared to Other Physiotherapy in Patients with Parkinson’s Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Objective: We aim is to assess the efficacy of Lee Silverman Voice Treatment-BIG therapy (LSVT-BIG) compared to other physiotherapy in patients with Parkinson's Disease (PwP).…Updated Meta-analysis Assessing GLP-1 Agonists for Parkinson’s Disease
Objective: Evaluate the efficacy and safety of Glucagon-like peptide-1 (GLP-1) agonists on Parkinson’s disease (PD). Background: The idea of repositioning drugs used to treat PD…Botulinium toxin in treatment of Parkinsonism
Objective: This review discusses the use of BT in various motor and non-motor symptoms of Parkinsonism. This review discusses the use of BT in various…Boosting Education and Awareness Together for people with Parkinson’s Disease (BEATs-PD): Methodological Considerations in Research Co-Creation
Objective: To describe methodological considerations related to stakeholder engagement in community-based participatory research (CBPR) to create a dance and music-based program (DMBP) for people with…Effects of Exogenous Melatonin on Sleep and Motor Symptoms in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To evaluate melatonin's efficacy in enhancing sleep and motor symptoms in Parkinson’s disease (PD) through an updated systematic review and meta-analysis. Background: Sleep disturbances…Artificial Intelligence for Understanding Parkinson Disease State and Patient Stratification Using CSF Proteomics
Objective: The objective of this research is to employ an Artificial Intelligence (AI) approaches to identify patient status and disease states in neurodegenerative diseases (NDDs),…
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