Cerebral metabolic network in PLA2G6-associated parkinsonism
Objective: To characterize the cerebral metabolic network in PLA2G6-associated parkinsonism (PLA2G6-P). Background: PLA2G6-associated neurodegeneration is known as a continuum of phenotypes. Patients with late-onset PLA2G6-associated…Associations between Choroid Plexus and tau in Parkinson’s Disease
Objective: To investigate the associations between the choroid plexus (ChP) and protein indicators of Parkinson’s Disease (PD). Background: The ChP is the primary organ that…Classification of Parkinson’s disease using AI based on multi-modal brain MRI connectomics
Objective: To develop a novel artificial intelligence (AI) model using connectivity matrices derived from multi-modal brain magnetic resonance imaging (MRI) to aid diagnosis and subtyping…Dopamine transporter imaging to predict the risk of aspiration in patients with Parkinson’s disease
Objective: To assess the predictive performance of clinical measures, including dopamine transporter (DaT) imaging, for identifying aspiration risk in patients with Parkinson’s disease (PD). Background:…Neurovascular Involvement in Parkinson’s Disease Cognitive Impairment: A 4D Flow Study
Objective: To investigate the cerebrovascular contribution to cognitive decline in Parkinson’s disease (PD). Background: Cognitive impairment is a major non-motor feature of PD. Accruing evidence…Associations Between Striatal Dopamine Transporter Binding and Motor Asymmetry In De Novo PD with and Without RBD
Objective: To evaluate the associations between striatal and motor asymmetry in Parkinson’s disease with probable RBD compared to without. Background: Parkinson’s disease is typically characterized…MIBG Uptake in the Major Salivary Glands in Patients with Parkinson’s Disease and Dementia with Lewy Bodies
Objective: The aim of the study was to compare the metaiodobenzylguanidine (MIBG) uptake in the major salivary glands (MSG) in patients with Parkinson’s disease (PD)…Increased Brain-Age Gap Estimate (BrainAGE) in Neurological Wilson Disease
Objective: To assess grey matter (GM) volume derived brain-aging in Wilson Disease (WD) using a previously proposed machine learning (ML) algorithm. Background: GM atrophy is…TM9SF2 Knockdown Decreases Pathological Alpha-synuclein Aggregation In Vivo
Objective: To determine whether knockdown of transmembrane 9 super family 2 (TM9SF2) decreases the formation of alpha-synuclein inclusions and toxicity to nigral neurons in the…Assessment of Motor and Non-Motor Alterations Impacting Functionality in Parkinson’s Disease Patients
Objective: To investigate the impact of motor and non-motor changes on the functionality of individuals with Parkinson's disease Background: Parkinson's disease (PD) is the second…
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