MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2024 International Congress

    Resting-State Network Alterations in Patients with Isolated REM Sleep Behavior Disorder and their Association with Clinical Symptoms

    I. Roura, J. Pardo, J. Oltra, A. Campabadal, Y. Compta, N. Bargallo, M. Serradell, C. Junqué, A. Iranzo, B. Segura (Barcelona, Spain)

    Objective: To characterize brain functional connectivity (FC) in patients with isolated REM sleep behavior disorder (iRBD) and its associations with clinical features. Background: Patients with…
  • 2024 International Congress

    Whole-brain functional network signature reflecting conversion of isolated REM sleep behavior disorder

    XJ. Dan, L. Gao, J. Ma, T. Wu, P. Chan (Beijing, China)

    Objective: The aim was to investigate the brain functional network alteration /pattern as a measure to identify the conversion from idiopathic rapid eye movement sleep…
  • 2024 International Congress

    Longitudinal change in brain function and structure related to plasma neurofilament light protein in early-stage Parkinson’s disease

    Y. Xiao, SC. Wang, YB. Hou, HF. Shang (Chengdu, China)

    Objective: We aimed to explore the relationship between the pNfL and change in the brain in early-stage PD using a longitudinal brain imaging cohort. Background:…
  • 2024 International Congress

    Motion-robust high-resolution imaging of nigrosome-1 in Parkinson’s disease

    M. Skorpil, O. Norbeck, P. Svenningsson, S. Skare, A. van Niekerk (Stockholm, Sweden)

    Objective: To develop a motion-insensitive high-resolution susceptibility weighted imaging (SWI) sequence for evaluating nigrosome-1 in substantia nigra. Background: In Parkinson's disease (PD) increased amounts of…
  • 2024 International Congress

    Neural Correlates of Dual Task Touchscreen Performance in Parkinson’s Disease

    J. de Vleeschhauwer, N. D'Cruz, I. Orlando, J. Tan, E. Nackaerts, W. Vandenberghe, S. Lewis, M. Shine, A. Nieuwboer (Leuven, Belgium)

    Objective: To compare task-related brain activity during a touchscreen task in Parkinson’s disease (PD) patients and healthy controls (HC) in single (ST) and dual task…
  • 2024 International Congress

    Cortical morphometry and subcortical volumetry in motor subtypes of Parkinson’s disease

    P. Pal, S. Prasad, T. Nagaraj, S. Bhat, S. Purushotham, R. Taneja, V. Holla, R. Mahale, N. Kamble, R. Yadav, J. Saini (Bengaluru, India)

    Objective: This study aims to evaluate the presence of differences in cortical morphometry and subcortical volumetry in tremor dominant Parkinson’s disease (TDPD) and postural instability…
  • 2024 International Congress

    Mapping the distribution of neurotransmitters to resting-state functional connectivity in patients with Parkinson’s disease

    W. Li, N. Lao-Kaim, R. Li, A. Martín-Bastida, A. Roussakis, G. Searle, N. Valle-Guzman, V. Dayal, D. Athauda, Z. Kefalopoulou, P. Mahlknecht, A. Church, K. Peall, H. Widner, G. Paul, T. Foltynie, R. Barker, P. Piccini (London, United Kingdom)

    Objective: To examine the associations between functional connectivity (FC), as measured by resting-state functional magnetic resonance imaging (rs-fMRI), and the spatial distribution of dopamine and…
  • 2024 International Congress

    Hippocampal volume in Parkinson’s Disease in south India

    R. Kandadai, T. Syed, A. Arora, T. Sd, S. Kola, S. Yaranagula, V. Prasad, R. Alugolu, S. Turaga, R. Borgohain (Hyderabad, India)

    Objective: To analyse hippocampal volume differences among the patients with Parkinson’s disease and healthy individuals. Background: In humans, hippocampus is involved in regulation of emotions,…
  • 2024 International Congress

    Development of an AAV-mediated artificial miRNA targeting human alpha-synuclein (α-syn) as a potential gene therapy for Synucleinopathies

    S. Basu, V. Singh, N. Gattone, J. Li, B. Wicks, X. Huang, E. Fabyanic, S. Wang, M. Li, X. Qian, G. Rivera-Pena, C. Li, Z. Yu, P. Raman, E. Kostuk, MG. Biferi, E. Ramsburg (Philadelphia, USA)

    Objective: To develop an adeno-associated virus (AAV)-based artificial miRNA (miRNA) system targeting human α-syn. Background: Synucleinopathies such as Parkinson’s disease (PD) and Multiple System Atrophy…
  • 2024 International Congress

    Case Report Increasing ‘On-time’ Using Mucuna pruriens Concomitantly with Traditional Levodopa/carbidopa Management

    T. Denne (United States, USA)

    Objective: Case study to see if concomitant use of the botanical Mucuna pruriens with traditional levodopa/carbidopa management could improve patient ‘off-time.’ Background: Mucuna pruriens is a pantropical legume…
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