Resting-State Network Alterations in Patients with Isolated REM Sleep Behavior Disorder and their Association with Clinical Symptoms
Objective: To characterize brain functional connectivity (FC) in patients with isolated REM sleep behavior disorder (iRBD) and its associations with clinical features. Background: Patients with…Whole-brain functional network signature reflecting conversion of isolated REM sleep behavior disorder
Objective: The aim was to investigate the brain functional network alteration /pattern as a measure to identify the conversion from idiopathic rapid eye movement sleep…Longitudinal change in brain function and structure related to plasma neurofilament light protein in early-stage Parkinson’s disease
Objective: We aimed to explore the relationship between the pNfL and change in the brain in early-stage PD using a longitudinal brain imaging cohort. Background:…Motion-robust high-resolution imaging of nigrosome-1 in Parkinson’s disease
Objective: To develop a motion-insensitive high-resolution susceptibility weighted imaging (SWI) sequence for evaluating nigrosome-1 in substantia nigra. Background: In Parkinson's disease (PD) increased amounts of…Neural Correlates of Dual Task Touchscreen Performance in Parkinson’s Disease
Objective: To compare task-related brain activity during a touchscreen task in Parkinson’s disease (PD) patients and healthy controls (HC) in single (ST) and dual task…Cortical morphometry and subcortical volumetry in motor subtypes of Parkinson’s disease
Objective: This study aims to evaluate the presence of differences in cortical morphometry and subcortical volumetry in tremor dominant Parkinson’s disease (TDPD) and postural instability…Mapping the distribution of neurotransmitters to resting-state functional connectivity in patients with Parkinson’s disease
Objective: To examine the associations between functional connectivity (FC), as measured by resting-state functional magnetic resonance imaging (rs-fMRI), and the spatial distribution of dopamine and…Hippocampal volume in Parkinson’s Disease in south India
Objective: To analyse hippocampal volume differences among the patients with Parkinson’s disease and healthy individuals. Background: In humans, hippocampus is involved in regulation of emotions,…Development of an AAV-mediated artificial miRNA targeting human alpha-synuclein (α-syn) as a potential gene therapy for Synucleinopathies
Objective: To develop an adeno-associated virus (AAV)-based artificial miRNA (miRNA) system targeting human α-syn. Background: Synucleinopathies such as Parkinson’s disease (PD) and Multiple System Atrophy…Case Report Increasing ‘On-time’ Using Mucuna pruriens Concomitantly with Traditional Levodopa/carbidopa Management
Objective: Case study to see if concomitant use of the botanical Mucuna pruriens with traditional levodopa/carbidopa management could improve patient ‘off-time.’ Background: Mucuna pruriens is a pantropical legume…
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