Enlarged Perivascular Spaces in the Temporal Lobe as a Predictor for Incident Dementia in Parkinson’s Disease
Objective: To evaluate the whether regional burden of enlarged perivascular space (EPVS) hold prognostic value in predicting the dementia conversion in Parkinson's disease (PD). Background:…Regional Brain Volume Differences Across PD Clinical Subtypes
Objective: To investigate brain morphometric differences across Parkinson disease (PD) clinical subtypes. Background: We developed a PD subtype classification with three subtypes that includes motor…Characterization of a Novel alpha-synuclein PET radiotracer, [18F]C05-05, in a PPMI Sub-study
Objective: Characterization of the PET radiotracer, [18F]C05-05, in the PPMI Study Background: Validation of imaging biomarkers in Parkinson disease (PD) is a major objective of…AI based longitudinal changes in substantia nigra contrast and volume on neuromelanin MRI and its relation to clinical markers in a multi-site Parkinson’s disease study.
Objective: To apply an AI model in a multi-site longitudinal study to segment substantia nigra pars compacta (SNpc), perform longitudinal analysis, and quantify its association…[18F]PR04.MZ PET CT as a clinical tool in the differential diagnosis of PD and other atypical parkinsonian syndromes in the first 5 years of symptoms
Objective: Investigate if the [18F]PR04.MZ PET CT is a useful tool in the differential diagnosis of PD and atypical parkinsonian syndromes (AP), mainly MSA and…Automated Imaging Differentiation of Parkinsonism (AIDP): A Prospective 21-site Trial within the Parkinson’s Study Group
Objective: To prospectively test the performance of Automated Imaging Differentiation of Parkinsonism (AIDP), a machine learning based diagnostic biomarker software for Parkinson’s disease (PD), multiple system atrophy Parkinsonian…A Kinematic and fMRI Study of the Neural Correlates of Bradykinesia in Parkinson’s Disease
Objective: This study aimed at investigating the neural and kinematic correlates of bradykinesia during hand-tapping in people with Parkinson’s disease (pwPD) relative to healthy controls.…Untargeted Serum Metabolomics Identifies Glycine-Serine Metabolism Disruption as Biochemical Bignature in Parkinson’s Disease
Objective: We attempted to identify a metabolomic signature distinctive of Parkinson’s disease (PD) through an untargeted metabolomics approach. Background: Using an high-performance liquid chromatography targeted…Spray with Nasal Mucoadhesive Microspheres for Treating Parkinsonism.
Objective: Although levodopa is the preferred medication for treating Parkinson's disease, it has a very poor brain absorption and limited oral bioavailability. The goal of…Augmented feedback during virtual reality training improves learning in people with Parkinson’s disease: A Single-Blind Randomized Clinical Trial
Objective: This study aims to compare the effects of AF during VR training on motor learning in PPD. Background: Augmented feedback (AF) can enhance the learning…
- « Previous Page
- 1
- …
- 435
- 436
- 437
- 438
- 439
- …
- 1942
- Next Page »