Mapping Cholinergic Signaling in Parkinson Disease Using [18F]VAT
Objective: To determine how cholinergic signaling changes within Parkinson Disease (PD) and how these differences relate to the progression of cognitive and behavioral symptoms. Background:…Predicting Freezing of Gait (FoG) in Parkinson’s Disease from Conventional T1-Weighted MRI
Objective: To predict freezing of gait in individuals with Parkinson's disease using T1-weighted MRI and machine learning techniques. Background: Freezing-of-gait (FoG) is a debilitating condition…Differences in regional activity levels between healthy controls, PD-nFOG, and PD-FOG as measured by ALFF and fALFF using resting-state fMRI.
Objective: To elucidate regional neural activity differences in patients with PD-FOG using resting-state fMRI (rs-fMRI). Background: Freezing of gait (FOG) in Parkinson's disease (PD0 is…Naturalistic walking in Parkinson’s disease: Prefrontal cortex activity measured with functional near-infrared spectroscopy (fNIRS)
Objective: In persons with Parkinson’s disease (PwPD), to observe brain activity in prefrontal cortex (PFC) using fNIRS during naturalistic walking that mimics everyday scenarios1, with…Serotonergic dysfunction and impulse control disorders in Parkinson’s disease: a double-tracer PET study
Objective: To investigate the dysfunction of the serotonergic system related to impulse control disorders in patients with Parkinson’s disease. Background: Impulse control disorders (ICDs, including…Longitudinal Structural and Functional Correlates of Progression in Isolated Rapid Eye Movement Sleep Behaviour Disorder
Objective: To identify progressive structural and functional imaging alterations in a longitudinal cohort of patients with isolated rapid eye movement sleep behavior disorder (iRBD). Background:…Habenular Structural Connectivity Changes in Parkinson’s Disease: A 7T MRI Study
Objective: To assess if the structural connectivity of habenula (Hb) differs between Parkinson’s disease (PD) patients and healthy controls (HCs). Background: PD is marked by…Functionality Analysis of Immunoregulatory Cells Stimulated with Dopaminergic Agonists in People Living with Parkinson’s Disease
Objective: To evaluate the effect of dopaminergic agonists (DA) on the activation and functionality of regulatory cells in People living with Parkinson's Disease (PwP). Background:…Attitudes and Beliefs Towards Medication Burden and Deprescribing in Parkinson Disease
Objective: To examine the attitudes and beliefs about medication burden and deprescribing among persons living with Parkinson disease (PD) Background: Deprescribing of potentially inappropriate medications…Developing a Virtual Brick-Building Group for Veterans with Movement Disorders
Objective: To improve quality of life for Veterans with movement disorders by creating a virtual group using building bricks Background: Parkinson’s disease (PD) may cause…
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