Reliability of Digital Measures in Parkinson’s Disease and Their Implications for Sample Size Calculations
Objective: Assess the reliability and measurement error of measures derived from digital health technologies (DHTs) in Parkinson’s Disease (PD) patients and estimate sample size for…How many days are required to reliably estimate diverse digital mobility outcomes from various gait domains with a lower back sensor in people with Parkinson’s disease?
Objective: To determine the number of days needed to obtain reliable, diverse digital mobility outcomes (DMOs) from daily activity recordings obtained using a lower back,…A non-linear index can detect early postural instability in people with Parkinson’s disease: Enhancing perspectives on the utilization of cost-effective technologies.
Objective: To investigate the effectiveness of a non-linear index for identifying the decline in postural control associated with PD progression. Background: Postural instability is a…Speech Biomarkers for Dysarthria in Parkinson’s Disease — Clinical Validation Across two Languages
Objective: To identify reliable speech biomarkers for assessing dysarthria in individuals with Parkinson's disease (PD) and ensuring their clinical validity across languages. Background: This study…Codesigning Tech with Patients – Insights from the Quantitative and Qualitative Analysis of Three Technologies used in Patients With Parkinson’s Disease
Objective: To evaluate the usability and acceptability of three different digital health technologies developed for Parkinson's disease (PD). Background: PD care requires meeting patients' changing…Smartwatch-Based Screening to Identify Candidates for Deep Brain Stimulation in Parkinson’s Disease
Objective: To use smartwatches to identify candidates for deep brain stimulation (DBS). Background: DBS can meaningfully lessen Parkinson's disease (PD) motor symptoms and improve quality…Focused Ultrasound Thalamotomy for Tremor-Dominant Parkinson Disease – Ablation Volume and Dentatorubrothalamic Tract Overlap Does Not Predict Outcome
Objective: To report the long-term outcomes in Tremor-Dominant Parkinson Disease (TDPD) after a unilateral Focused Ultrasound (uni-FUS) thalamotomy and explore factors that may predict the…Clinical effectiveness and safety of staged-bilateral MRgFUS for treating essential tremor, a literature review
Objective: To perform a literature overview of the clinical effectiveness and safety of staged-bilateral MR-guided focused ultrasound (MRgFUS) in essential tremor. Background: In the brain,…A Curious Case of Copper de-Compensation
Objective: To describe the investigation and management of a patient with Wilson’s disease who experienced late-onset neurological deterioration despite continued treatment. Background: Wilson’s disease is…Effect of Levodopa therapy in Hypokinetic Dysarthria in Parkinson’s Disease
Objective: The objective of this study was to assess the possible changes in acoustic speech parameters in a cohort of PD patients after acute levodopa…
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