Abnormal brain iron metabolism influences neural function in isolated laryngeal dystonia
Objective: To investigate iron accumulation as a pathophysiological signature of laryngeal dystonia (LD) and assess the abnormal influence of iron on neural activity within the…Severe Acute Spinal Cord Injury Due to Isolated Generalized Dystonia
Objective: To report a case of isolated generalized dystonia causing severe cervical trauma Background: Rotational forces on the cervical spine leading to injury is a…Increased cerebellar grey matter in writer’s cramp patients: a morphometric signature of symptom compensation
Objective: This study focused on grey matter changes in the cerebellum by performing voxel-based morphometry (VBM) on infratentorial MRI scans of writers' cramp (WC) patients,…Precision Functional Mapping of Therapeutic Response in Task-specific Focal Dystonia
Objective: To precisely characterize patient-specific connectivity changes in response to botulinum toxin injection. Background: Adductor laryngeal dystonia (ADLD) is a type of task-specific focal dystonia…Cervical dystonia after cerebellar stroke and medullary hemorrhage
Objective: to present a patient who developed delayed secondary cervical dystonia after anterior medullary hemorrhage and ipsilateral cerebellar stroke. Background: Postroke dystonia is mostly associated…Effect Of Botulinum Toxin On Non-Motor Symptoms In Adult-Onset Idiopathic Focal Dystonia
Objective: To assess the effect of Botulinum toxin on non-motor symptoms and quality of life in patients with adult-onset idiopathic focal dystonia. Background: A broad…Reversible Hemichorea-Hemiballismus-Hemifacial Spasm in Diabetic Striatopathy
Objective: Nonketotic hyperglycemia (NKH), also known as Diabetic Striatopathy (DS) can present with different involuntary movements in diabetic patients. Hemichorea-hemiballismus (HC-HB) is the most common…Clinical and Genetic Profile of Spinocerebellar Ataxias in a Tunisian Cohort
Objective: Our aim was to determine the clinical, genetic and radiological characteristics of spinocerebellar ataxias (SCA) in a Tunisian cohort. Background: SCA is a heterogenous…Long-term follow up of unilateral deep brain stimulation for Parkinson’s disease
Objective: To assess long-term effectiveness of unilateral Deep Brain Stimulation (DBS) in Parkinson’s disease (PD) patients with up to 14 months of follow-up Background: DBS…Rationale for LRRK2 inhibition in sporadic Parkinson’s disease and the LUMA trial
Objective: To summarize the rationale for LRRK2 inhibition in sporadic PD patients without LRRK2 mutations, and to describe the current design of the LUMA study,…
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