Comparison in Therapeutic Outcome of Ultrasound-Guided Botulinum Injections for Limb Spasticity Versus Dystonia
Objective: To compare the therapeutic efficacy of BT injections for spasticity and dystonia in the limbs. Background: Botulinum toxin (BT) shows promise in alleviating limb…Clinical and Genetic Characteristics in a Chinese Cohort of Complex Spastic Paraplegia Type 4
Objective: To delineate the genotypic and phenotypic spectrum of patients with complex SPG4 phenotype and further explore genotype-phenotype correlations. Background: Spastic paraplegia type 4 (SPG4),…The Clinical and Genetic Characteristics of HSP Patients by WES Sequencing Combined with MLPA
Objective: We aim to clarify the phenotype and gene spectrum of hereditary spastic paraplegia (HSP) and improve the molecular diagnosis. Background: Next-generation sequencing-based molecular assessment…Benzodiazepines in the Management of Restless Legs Syndrome: A Systematic Review and Meta-Analysis
Objective: To evaluate the efficacy and safety of benzodiazepines (BZD) as treatment for Restless Legs Syndrome (RLS), compared to placebo or other drugs. Background: RLS…Mechanism Study of Familial Cortical Myoclonic Tremor with Epilepsy Type 1 Caused by Pentanucleotide Repeat Expansion in the SAMD12 Gene
Objective: This study aims to explore the pathogenic mechanisms of familial cortical myoclonic tremor with epilepsy (FCMTE) using various cellular models, from the perspectives of…Genetic Migration Dynamics: Unraveling the Influence of Internal Migration on Huntington’s Disease Prevalence in the Amazonas State.
Objective: In this study, we investigate the influence of internal migration within Brazil on the prevalence of Huntington's disease in the state of Amazonas. Background:…Transcranial magnetic stimulation target comparison identifies motor network reorganization associated with behavioral improvement in writer’s cramp dystonia
Objective: This study aims to reveal the motor network effects of repetitive transcranial magnetic stimulation (rTMS) in Writer's cramp (WC) subjects that correspond to behavioral efficacy.…Rapid Onset Kinematic Effects of Thalamic/Subthalamic DBS in Cervical Dystonia
Objective: To assess the acute effect of combined ventrolateral thalamus (VL-Th) and subthalamic nucleus (STN) stimulation in Cervical Dystonia (CD) on clinical and kinematic measurements…A non-linear index can detect early postural instability in people with Parkinson’s disease: Enhancing perspectives on the utilization of cost-effective technologies.
Objective: To investigate the effectiveness of a non-linear index for identifying the decline in postural control associated with PD progression. Background: Postural instability is a…Mapping the distribution of neurotransmitters to resting-state functional connectivity in patients with Parkinson’s disease
Objective: To examine the associations between functional connectivity (FC), as measured by resting-state functional magnetic resonance imaging (rs-fMRI), and the spatial distribution of dopamine and…
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