Longitudinal CSF measurements of alpha-synuclein, amyloid beta and tau in Parkinson disease
Objective: To evaluate whether cerebrospinal fluid (CSF) levels of alpha synuclein (Asyn), amyloid beta (Aβ) and tau change with disease progression and to evaluate whether…Is a Parkinson’s Sialorrhoea service effective?
Objective: Evaluate the efficacy and tolerance of Botulinum Toxin A (BoNT A) in managing sialorrhoea in People with Parkinsons (PwP)Assess impact on quality of life…Experience of Quality of Life in German Persons living with Parkinson’s Disease: A Qualitative Exploration
Objective: It seems essential to understand how people with Parkinson´s disease (PwPD) experience quality of life (QoL) and to which domains they assign particular importance.…Trial site factor in Parkinson’s disease (PD) diary non-compliance
Objective: In this analysis, we wanted to explore if PD diary non-compliance is distributed randomly in the dataset or if it has a tendency to…Olfactory neurons’ Substance P is highly expressed in Parkinson’s disease reflecting gastrointestinal dysfunction
Objective: To elucidate the role of Substance P in PD through molecular characterization of patients’ olfactory neurons. Background: Substance P is a neuropeptide largely expressed…Does Cognitive Complaint in Parkinson’s Disease Reflect in Neuropsychological Testing?
Objective: To investigate whether the neuropsychological tests differ among participants with Parkinson’s disease (PD) presenting with the subjective cognitive complaint (PD-SCC) and PD with normal…An Algorithmic Approach to Assessing Cognitive Functioning in Individuals with REM Sleep Behavior Disorder
Objective: To apply an algorithmic approach to interpretation of cognitive data to assess cognitive impairment in RBD participants. Background: Cognitive changes in emerging neurodegenerative disease…DaT-Scans Have Limited Utility in Predicting Treatment Response to Ventriculoperitoneal Shunts in Normal Pressure Hydrocephalus
Objective: To determine usefulness of DaT-SPECT imaging in the management of normal pressure hydrocephalus (NPH). Background: Dopamine transporter single-photon emission computed tomography (DaT-SPECT) imaging is…Subjective cognitive complaints in participants of the Healthy Brain Ageing (HeBA) study
Objective: To investigate the prevalence of subjective cognitive complaints (SCC) from Healthy Brain Ageing Study (HeBA) participants in Luxembourg, and explore risk factors prevalence which…modulation of sodium potassium ATPase activity by norepinepherine and serotonin to find an effective cure of parkinson’s disease by introducing the novel concept of insilico drug repurposing
Objective: Parkinson's disease can cause neuropsychiatric disturbances which can range from mild to severe. This includes disorders of speech, cognition, mood, behaviour, and thought. In addition to…
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