Characterization of gastrointestinal dysfunction in Parkinson’s by disease stage
Objective: To conduct a comprehensive cross-sectional and longitudinal characterization of gastrointestinal dysfunction (GID) in Parkinson’s disease (PD). Background: GID is an important feature of PD…Medication safety in Parkinson’s disease patients: evaluation of recommendations for decision support in the national drug-disease interaction database
Objective: Objective: Drug-disease interactions in Parkinson's disease patients can give rise to situations where a drug may have negative effects on both motor- and non-motor…The potential role of Per- and Polyfluoroalkyl Substances (PFAS) in movement disorders: Implications and Risk assessment to Human Health
Objective: The objective of our study is to critically summarized the neurotoxicity of Perfluoroalkyl substances (PFAS) and linked this environmental pollutant with movement disorders and…Genetic determinants of early motor progression in Parkinson’s cohorts
Objective: To determine the genetic determinants of motor progression in Parkinson disease (PD) using genome-wide analysis correlated with the MDS-UPDRS Part III motor scale. Background:…Non-apoptotic caspase-3 activation mediates early synaptic dysfunction of indirect pathway neurons in the parkinsonian striatum
Objective: We set out to investigate whether caspase-3 plays a role in the loss of dendritic spines and the concomitant synaptic deficits that develop in…Pallidal Deep Brain Stimulation for Treatment of Poststroke Hemichorea
Objective: We report a case of medication-refractory poststroke hemichorea where deep brain stimulation of the globus pallidus internus (GPi-DBS) was utilized to alleviate hemichorea. Background:…The distinctive functional connectivity of the cholinergic nucleus basalis of Meynert in Parkinson’s disease across different motor subtypes
Objective: We aim to compare the state of cortical-NBM functional connectivity across healthy control (HC), PIGD-predominant PD (PIGD-PD), and tremor-dominant PD (TD-PD). Additionally, the correlation…Biochemical markers of glucocerebrosidase (GCase) deficiency in primary macrophages derived from GBA1 mutation carriers with and without Parkinson’s disease
Objective: The aim of the present study was to assess biochemical markers in primary macrophages that could distinguish patient with Parkinson’s disease linked to mutations…Blood Lipid Biomarkers in Early Parkinson Disease and Parkinson Disease with Mild Cognitive Impairment
Objective: This study aims to investigate the association between comprehensive blood lipid biomarkers and Parkinson's disease (PD). Background: Studies have shown that the serum levels…The Hidden Disease Burden and Treatment Experience of Patients with Essential Tremor: A Retrospective US Claims Analysis
Objective: To describe the attributes of patients with essential tremor (ET), associated comorbidities, and ET treatments using a US claims database. Background: ET is estimated…
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