DOPAMINERGIC AND NON-DOPAMINERGIC TREATMENT AFTER DEEP BRAIN STIMULATION (DBS) IN PARKINSON DISEASE (PD). IMPORTANCE OF NON MOTOR SYMPTOMS (NMS)
Objective: To analyse global pharmacological adjustment after Deep Brain Stimulation (DBS) in Parkinson's Disease (PD) patients, and secondarily its relation with Non Motor Symptoms (NMS).…Effect of simultaneous mGlu2 positive allosteric modulation and orthosteric stimulation combined with 5-HT2A antagonism on psychosis-like behaviours, dyskinesia and parkinsonism in the MPTP-lesioned marmoset
Objective: To assess the effects of concurrent metabotropic glutamate type 2 (mGlu2) positive allosteric modulation and orthosteric stimulation combined with serotonin type 2A (5-HT2A) antagonism.…Effect of H. pylori Infection on L-DOPA Pharmacokinetics in Patients with Parkinson’s disease.
Objective: To evaluate whether Helicobactor pylori (H.pylori) infection affects the pharmacokinetics of L-DOPA in patients with Parkinson’s disease (PD). Background: H. pylori infects gastric mucosa…A French national multicentric prospective study of the 1-year impact of STN-DBS on speech in Parkinson’s disease: profile of progression and prognostic factors.
Objective: 1) To describe the evolution of speech in a large cohort of patients before and 1 year after STN-DBS. 2) To search for preoperative…Long-term real-world effectiveness of carbidopa/levodopa enteral suspension after 36 months of treatment initiation: Final results from PROviDE study
Objective: To examine the real-world long-term effectiveness of carbidopa/levodopa enteral suspension (CLES) on off time and other patient reported outcomes (PROs) among advanced Parkinson’s disease…Effectiveness of opicapone in Parkinson’s disease patients with motor fluctuations according to baseline use of safinamide: findings from the real-world OPTIPARK study
Objective: This post-hoc analysis evaluated the effectiveness of opicapone (OPC) in Parkinson’s disease (PD) patients with motor fluctuations (MF) according to baseline use of safinamide…Combined Plantar Stimulations Using a Novel Parkinson Shoe benefit Parkinson’s Disease Patients with Unresponsive Freezing of Gait
Objective: To explore the effect of combined vibratory and pressure stimulations in PD patients with unresponsive FOG and develop the innovative PD shoe. Background: Freezing…Opicapone in clinical practice in Parkinson’s disease patients with motor fluctuations and complications of therapy at baseline: findings from the OPTIPARK study
Objective: This post-hoc analysis evaluated the effects of opicapone (OPC) treatment in patients with Parkinson’s disease (PD) who experience motor fluctuations and complications of therapy…Effectiveness of opicapone in Parkinson’s disease patients with motor fluctuations according to baseline use of monoamine-oxidase-B inhibitors (MAO-B) and dopamine agonists (DA): findings from the real-world OPTIPARK study
Objective: This post-hoc analysis evaluated the effectiveness of opicapone (OPC) in Parkinson’s disease (PD) patients with motor fluctuations (MF) according to baseline use of monoamine-oxidase-B…Causes of deaths in patients with Parkinson’s disease in the era before the use of modern drug therapy and at the present time
Objective: to study the impact of modern pharmacotherapy of Parkinson's disease (PD) on the main causes of death. Background: the modern era of the use…
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