Mapping regional alpha-synuclein seeding capacity in Multiple System Atrophy
Objective: The objective of our work was to develop a novel high-throughput cell-free assay that allowed us to perform a comprehensive characterization of α-synuclein seeding…Natural History of Probable MSA in India: A Prospective Cohort Study
Objective: We aimed to prospectively study the natural history of probable multiple system atrophy (MSA) including autonomic testing, survival analysis; and assess whether serum alpha-synuclein…Longitudinal 18F-PBR06 (TSPO) and Volumetric MR Imaging as Pharmacodynamic Endpoints for MSA – Ongoing Investigator Sponsored Trial of Verdiperstat
Objective: In multiple system atrophy (MSA) patients to: 1) evaluate 18F-PBR06 positron emission tomography (PET) for longitudinal assessment of 18-kilodalton-translocator protein (TSPO) binding; 2) assess…Endoscopic Characteristics of Dysphagia in Multiple System Atrophy compared to Parkinson’s Disease
Objective: This study systematically assessed phenotypes of dysphagia in MSA compared to PD and correlated subjective dysphagia to objective endoscopic findings in MSA. Background: Dysphagia…Progression of nigro-striatal denervation in cerebellar Multiple System Atrophy: a prospective study
Objective: To study the progression of nigro-striatal denervation and evaluate the capacity for [123I]-FP-CIT-SPECT and parkinsonian signs to differentiate MSA-C from idiopathic late-onset cerebellar ataxia…Benign Progressive Supranuclear Palsy: mild pathology associated with parkinsonism
Objective: Objective: To describe the clinical presentation and neuropathology of cases where the degree of tau pathology is mild, and the neuronal loss is anatomically…An evaluation of the application of clinical research criteria for corticobasal degeneration in a large clinico-pathological series
Objective: To evaluate diagnostic criteria for corticobasal degeneration (CBD) in relation to pathology and disease course. Background: The overlapping features of CBD and related conditions…Predictors of survival in Progressive Supranuclear Palsy in a Tunisian cohort
Objective: To investigate survival and its determinants in a Tunisian cohort of Progressive Supranuclear Palsy (PSP). Background: PSP is a neurodegenerative tauopathy characterized by faster…Language impairment in Corticobasal Syndrome: from clinical phenotype to biomarkers
Objective: To investigate the language impairment profile of patients diagnosed as probable Corticobasal Syndrome (CBS) [1] in light of a multimodal imaging biomarkers analysis, namely…A retrospective review of clinical features of Progressive Supranuclear Palsy (PSP) in a movement disorders clinic
Objective: Understanding the common clinical features of PSP. Background: PSP is a relatively rare progressive neurodegenerative disease, which can often be difficult to distinguish from…
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