Comparative Effectiveness of Carbidopa/Levodopa Enteral Suspension and Deep Brain Stimulation on Pill Burden Reduction in Medicare Patients With Advanced Parkinson’s Disease
Objective: To evaluate real-world comparative effectiveness of Carbidopa/Levodopa Enteral Suspension (CLES) versus Deep Brain Stimulation (DBS) initiation on pill burden reduction in patients with Advanced…The effectiveness of home modification on gait and falling episode in Parkinson’s disease (PD) patients.
Objective: Identify the unsafe PD patients’ home who had gait problems and provide home modifications. Background: The motor impairments in PD also involve both appendicular…Limitations of conventional dopaminergic medication in advanced Parkinson’s disease: results from 127 patients treated with Levodopa Carbidopa Intestinal Gel
Objective: To evaluate the characteristics of the last conventional dopaminergic treatments in a large cohort of patients with advanced Parkinson’s Disease (APD) treated with Levodopa…Pilot study of Phenotype of Antisense-Oligonucleotide-(ASO)-knockdown of Cerebral-Dopamine-Neurotrophic-Factor (CDNF) as Parkinson Disease model : implications for PD and related Dementia Therapeutics
Objective: Our objective is twofold: 1)to examine whether CDNF-ASO paradigm can induce a unique phenotype mimicking PD/PDD/LBW in the rodent species; 2) to evaluate whether…CHAPERONIC PROPENSITIES OF AFRICAN WALNUT AS A THERAPEUTIC TARGET IN MANGANESE-INDUCED PARKINSON-LIKE NEUROPATHOLOGY IN WISTAR RATS
Objective: Herein, the chaperonic propensities of ethanolic extract of African walnut (WNE) in Manganese-induced Parkinson-like neuropathology in the prefrontal cortex and hippocampus was investigated. Background:…The Transcriptome from Multiple Regions of the MPTP-induced Parkinson’s disease Mouse Brain after exercise
Objective: To illuminate the respective functions of substantia nigra, striatum, cortex and cerebellum in Parkinson's motor improvement following exercise training in a chronic MPD (MPTP…Compensation strategies for gait impairment in Parkinson’s disease: a survey among 4,324 patients
Objective: The aim of this study was threefold: (1) to evaluate patients’ awareness and use of various compensation categories for gait impairments in PD; (2)…The gender gap in Parkinson’s disease before and after Subthalamic Nucleus Deep Brain Stimulation surgery: preliminary results of a retrospective study.
Objective: Gender differences in several neurodegenerative disorders have been extensively investigated. Nowadays, evidence and interest about sex-related distinctions regarding Parkinson's disease (PD) are increasing. The aim…Wearable sensor motor outcomes across patients with Parkinson’s disease from Asian, Black, and Caucasian ethnicity in the United Kingdom
Objective: To determine the effect of ethnic background on motor scores in people with Parkinson’s disease (PwP) using objective measurement. Background: Limited evidence has suggested…Local Field Potentials (LFP) used to guide treatment of biphasic dyskinesias in a patient with Parkinson’s Disease (PD)
Objective: To identify, characterize and treat dyskinesias and off time in a patient with PD via the use of gamma and beta peak LFP using…
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