Alteration of lysosomal enzymatic activities in patients with multiple system atrophy
Objective: To estimate whether alteration of lysosomal activities contributes to synucleinophaties pathogenesis. Background: Multiple system atrophy (MSA) belongs to a group of neurodegenerative disorders termed synucleinopathies, which also include Parkinson's disease (PD)…Cognitive assessment in a Greek cohort of Multiple System Atrophy patients.
Objective: The aim of the present study was to assess cognitive dysfunction in a Multiple System Atrophy (MSA) cohort and possible differences between disorder subtypes…Deep gray matter atrophy in MSA subtypes
Objective: To compare MRI parameters of atrophy in Multiple system atrophy (MSA) subtypes. Background: MSA is a rare adult-onset synucleinopathology that can be divided in…Non-invasive imaging markers of iron accumulation in Multiple System Atrophy
Objective: To define the localization and extent of iron accumulation in multiple system atrophy (MSA). Background: Elevated iron concentration in the basal ganglia has been…An Unusual Case of Multiple Systems Atrophy with Long Disease Duration, Severe Gliosis, and Scant Synuclein Pathology
Objective: To describe a pathologically unusual case of Multiple systems atrophy (MSA) with severe widespread gliosis and neuronal loss with scant alpha-synuclein (aSyn) pathology. Background:…Laryngeal Electromyography Findings in patients with Multiple System Atrophy
Objective: to systematically evaluate laryngeal electromyography findings, correlate them to laryngeal movement disorders assessed by a systematic task-protocol performed during FEES and clinical laryngeal symptoms.…Plasma Short-Chain Fatty Acids Differences in Multiple System Atrophy from Parkinson’s Disease
Objective: We aimed to investigate the plasma short-chain fatty acids (SCFAs) in multiple system atrophy (MSA) patients and to identify the potential differential diagnostic ability.…The Implications of Pyramidal Signs in Multiple System Atrophy
Objective: To determine pyramidal signs in multiple system atrophy (MSA) and the associations with other clinical characteristics. Background: The clinical manifestations of MSA are comprised…Mapping regional alpha-synuclein seeding capacity in Multiple System Atrophy
Objective: The objective of our work was to develop a novel high-throughput cell-free assay that allowed us to perform a comprehensive characterization of α-synuclein seeding…The effect of sleep positions on morning orthostatic hypotension in Multiple System Atrophy patients: A pilot study
Objective: To determine the effect of sleep position on morning OH in MSA patients Background: Dysautonomia is considered as one of the most distress symptom…
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