MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Effects of dopaminergic medication on reinforcement learning in Parkinson’s disease depend on depressive symptoms

    J. Tichelaar, C. Sayali, R. Helmich, R. Cools (Nijmegen, Netherlands)

    Objective: To investigate the effect of depression and dopaminergic medication on reinforcement learning (RL) in Parkinson’s disease. Background: Dopaminergic medication in PD is known to…
  • MDS Virtual Congress 2021

    Parkinson’s Disease, Cognitive Function and Medication Management: A Problem in Routine Care

    P. Tierney, O. Kaczmarek, A. Sethi, B. Bumstead, M. Buhse, E. Kravis, B. Anand, M. Zarif, M. Gudesblatt (Patchogue, USA)

    Objective: Explore the relationship between objective and patient-reported assessment of cognition to patient-reported medication management capabilities. Background: Parkinson’s disease (PD) is a complex neurodegenerative disorder…
  • MDS Virtual Congress 2021

    Statistical methods for dealing with missing data in longitudinal studies with application to Parkinson’s disease cognition research

    P. Zhang, S. Xie (Philadelphia, USA)

    Objective: To assess the performance of standard techniques for handling missing data in longitudinal studies under a variety of missing data scenarios. We demonstrate our…
  • MDS Virtual Congress 2021

    The study of genetic factors in motor levodopa-induced complications development in Russian patients with Parkinson’s disease

    G. Akhmadeeva, I. Khidiyatova, I. Gilyazova, G. Tayupova, S. Umutbaev, A. Baitimerov, R. Magzhanov (Ufa, Russian Federation)

    Objective: The aim of our study is to search for genetic risk factors for the development of motor side effects of dopaminergic therapy, such as…
  • MDS Virtual Congress 2021

    Identification of a new Homozygous mutation P.R258Q In the gene SYNJ1 of an Algerian consanguine (inbred) Family suffering from early onset atypical Parkinsonism

    M. Benmahdjoub, N. Nesrine, S. Bouchetara, A. Bessad, S. Lesage, A. Brice, M. Arezki, S. Kesraoui (Blida, Algeria)

    Objective: The purpose of this observation is to demonstrate that autosomal recessive early parkinsonism is clinically and genetically heterogeneous Background: Early Onset Parkinson’s disease is…
  • MDS Virtual Congress 2021

    The Global Parkinson’s Genetics Program (GP2) – a year’s progress

    C. Blauwendraat, A. Noyce, A. Reimer, B. Casey, E. Riley, B. Fiske, M. Rizig, J. Hardy, T. Foroud, K. Murphy, N. Wood, C. Wegel, A. Brice, S. Fox, P. Heutink, R. Krueger, N. Williams, T. Gasser, K. Mok, M. Sharma, K. Marek, T. Sherer, N. Mata, M. Nalls, E. Valente, H. Morris, C. Klein, A. Singleton, T. He-Global-Parkinson’S-Genetics-Program-(gp2) (Bethesda, USA)

    Objective: The Global Parkinson’s Genetics Program (GP2, http://gp2.org/) aims to dramatically expand the current understanding of the genetic architecture of Parkinson’s disease (PD) and to…
  • MDS Virtual Congress 2021

    EIF4G1 gene variants in a family affected by Parkinson´s disease

    C. Borrue (San Sebastián Reyes, Spain)

    Objective: Describe a novel mutation on a family affected by  Parkinson´s disease. Background: 46 years old woman. She came  to hospital complaining about  tremor and…
  • MDS Virtual Congress 2021

    Digenic R1441G-LRRK2 and Parkin mutations in Parkinson’s Disease: first clinicopathological case report.

    D. Campo-Caballero, A. Vinagre-Aragón, JF. Martí-Massó, A. Bergareche, A. Gorostidi, R. Ruiz-Onandi, J. Rodríguez-Antigüedad, J. Equiza, P. Iruzubieta-Agudo, I. Albajar, N. Sulibarria, J. Ruiz-Martinez (San Sebastián, Spain)

    Objective: To report a clinicopathological case of digenic PD with R1441G- LRRK2 and PRKN mutations. Background: Digenic inheritance of R1441G-LRRK2 and PRKN mutation is extremely…
  • MDS Virtual Congress 2021

    Parkinson’s-disease risk variants are differentially associated with discrete phenotypic characteristics of Parkinson’s-disease at baseline.

    B. Chase, A. Premkumar, B. Schoneburg, N. Kartha, J. Wei, H. Yu, A. Epshteyn, L. Garduno, A. Pham, R. Vazquez, R. Frigerio, D. Maraganore, K. Markopoulou (Skokie, USA)

    Objective: Evaluate whether genetic risk variants for Parkinson’s disease discovered in case-control GWAS uniformly or differentially contribute to the clinical phenotype of PD. Background: Genetic…
  • MDS Virtual Congress 2021

    The application of Next Generation Sequencing in the Parkinson Disease.

    E C. Chebbi (Tunis, Tunisia)

    Objective: This study aims to better investigating the pathogenetic of PD and improving the diagnostic approach in the molecular genetics, using the NGS. Background: Parkinson’s…
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