Quantitative measures of brain MRI as a predictive factor of cognitive outcomes after Subthalamic Nucleus Deep Brain Stimulation for Parkinson’s disease
Objective: To explore whether pre-surgical white matter lesion volume, measured quantitatively on brain MR images, is predictive of cognitive outcomes following subthalamic nucleus deep brain…Degree, onset and longevity of benefit achieved with Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) as assessed by the UPDRS.
Objective: To show the degree, onset and longevity of benefit achieved with STN DBS at our center. Background: At our center, we administer the UPDRS-III…Comparison of subthalamic and pallidal deep brain stimulation in treatment of Parkinson’s disease: a 5-year follow-up study
Objective: To assess and compare the long-term motor and functional outcome of subthalamic (STN) and pallidal (GPi) deep brain stimulation (DBS) in treatment of patients…A Novel Deep Brain Stimulation Programming Paradigm for Parkinson’s disease
Objective: To report the outcome of a novel interleaving stimulation (ILS) DBS programming paradigm (PP). Background: DBS of the STN using conventional high frequency (130-185Hz)…Excellent Non-motor Responses after Bilateral Subthalamic Deep Brain Stimulation in Parkinson’s Disease Patient with SNCA Duplication
Objective: We report a case of Parkinson's disease patient with SNCA duplication, who showed excellent response in both motor and non-motor symptoms after bilateral subthalamic stimulation. Background:…Deutetrabenazine is Associated with an Improvement in Involuntary Movements in Patients With Tardive Dyskinesia as Seen by the High Proportion of Responders to Deutetrabenazine Treatment in the AIM-TD Study
Objective: To examine response rates between patients receiving deutetrabenazine and placebo. Response levels were pre-specified from 10–90% improvement from baseline in Abnormal Involuntary Movement Scale…Laryngeal Tardive Dyskinesia in a Patient treated with Haldol
Objective: To describe the case of woman with post stroke hemiballism treated chronically with Haldol who developed laryngeal tardive dystonia and to review the current…Glucocerebrosidase mutations in idiopathic REM sleep disorder
Objective: Several studies have shown that glucocerebrosidase gene (GBA) mutations are strongly associated with the development of Lewy body diseases (LBD) and that idopathic REM…The neural correlates of apathy in premanifest and manifest Huntington’s disease: A cross-sectional multimodal imaging study
Objective: To delineate the brain correlates of apathy severity by means of glucose metabolism (18-FDG PET), grey-matter (GM) and white-matter (WM; FA-DTI) changes and relations…Update on the MDS-Sponsored Systematic Review On Clinical Rating Scales for Huntington’s Disease: motor, cognitive, functional ability and quality of life domains
Objective: To provide an update on the MDS-sponsored Systematic Review of Rating Scales for Huntington’s Disease (HD). Background: The use and validity of clinical rating…
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