The impact of gastric acid suppressants and antacids on levodopa plasma concentration in patients with Parkinson’s disease
Objective: The levodopa tablet is prone to dissolve in acidic conditions. We investigated whether gastric acid suppressants (histamine-2 receptor antagonists or proton pump inhibitors) and…Effect Of Non-Invasive Vagus Nerve Stimulation In Freezing And Oxidative Stress In Parkinson’s Disease Patients
Objective: In this observational pilot study we explored the long term effect of Non-Invasive VNS to improve the FOG and reduce oxidative stress in PD…Improving Racial and Ethnic Diversity in Parkinson`s Disease Clinical Trials
Objective: To identify and overcome challenges to recruiting minorities in Parkinson's Disease experimental therapeutic trials. Background: Inadequate representation of ethnic and minority population poses substantial…ND0612 (levodopa/carbidopa for subcutaneous infusion) achieves stable levodopa plasma levels when administered in low and high doses in patients with PD
Objective: Characterize the levodopa pharmacokinetic profile derived from continuous subcutaneous (SC) administration of ND0612. Background: Continuous levodopa/carbidopa (LD/CD) infusion is considered the optimal delivery route…Programming of deep brain stimulators in Parkinson’s disease with early motor complications (EARLYSTIM-study)
Objective: Recently the EARLYSTIM study showed the superior effect of subthalamic stimulation to best medical treatment in Parkinson`s disease with early motor complications. Background: EARLYSTIM…Manual and Verbal guidance during the balance training based in virtual reality is essential for therapeutic results in people with Parkinson’s disease: a randomized clinical trial
Objective: To compare the effects of balance training in Virtual Reality (VR) supported by manual and verbal guidance (MVG) versus an identical training in absence…The effect of dance and Nordic Walking on balance, gait and motor function in Parkinson’s disease
Objective: To present two rehabilitation programs based on dance and Nordic Walking (NW) for patients with Parkinson’s disease (PD) and their effects. Background: Parkinson’s disease…Interactions between amyloid-β and microglial activation in Parkinson’s disease
Objective: To evaluate the relationship between microglial activation and amyloid-β deposition in the brain using positron emission tomography (PET) in Parkinson’s disease (PD) with normal…Beta oscillatory changes during practice and retention of motor skills in healthy subjects and patients with PD
Objective: The objective is to define the relationship between increase in beta oscillatory changes with practice and retention of motor skills in normal healthy subject…Associations of DAT SPECT and TCS with prodromal features of Parkinson’s disease: results in PREDICT-PD participants
Objective: To examine whether changes on dopamine reuptake transporter (DAT) SPECT and transcranial sonography (TCS) correlated with Parkinson’s disease (PD) risk scores and other prodromal…
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