Using Vision to Predict Dementia in Parkinson’s Disease
Objective: To identify visual measures that relate to higher risk of dementia in Parkinson’s Disease (PD). Background: Dementia affects 50% of people with PD within…The development of an instrument for measuring Parkinson’s patient empowerment
Objective: To develop a valid and reliable measurement scale of Parkinson’s patient empowerment index (PPEI). Background: Patient empowerment concept has been used as part of…Change of Cognition Functions after Subthalamic Nucleus-Deep Brain Stimulationin in Parkinson’s Disease
Objective: To explore the changes of cognitive function in Parkinson disease (PD) patients with deep brain stimulation (DBS) of the subthalamic nucleus (STN). Background: STN-DBS…Adult neurogenesis is impaired in pink1-/- zebrafish (Danio rerio)
Objective: To determine whether PINK1 deficiency impairs adult neurogenesis in a tractable vertebrate model of PINK1-related Parkinson's disease (PD). Background: PD is characterized by loss…Mitochondrial phenotype related to the A30P alpha-synuclein mutation as a patient-derived cellular model of Parkinson’s disease
Objective: Our study aims to perform detailed phenotyping of the A30P alpha-synuclein familial case of PD, allowing to identify underlying mechanisms of the disease that…A review of modifiers of Parkinsonism in the Leucine-rich repeat kinase 2 (LRRK2) population
Objective: To review and examine the most current identified modifiers of Parkinsonism in the LRRK2 population. Background: LRRK2 is a protein with multiple domains and…Higher Levels of Serum Uric Acid Associated with Motor & Non-Motor Symptoms in Early Parkinson’s Disease
Objective: Uric acid (UA) has been shown to be potentially neuroprotective in Parkinson's disease (PD), a progressive neurodegenerative disorder that is clinically characterised by motor…Identification and analysis of differential miRNA in exosomes of dopaminergic neurons overexpressing α-synuclein
Objective: The aim of this study was to compare the miRNA expression in secreted exosomes from dopaminergic neurons overexpressing α-synuclein with healthy neurons. Background: Exosomes,…White Matter Hyperintensities and Mortality among Patients with Parkinsonism in Olmsted County, MN (1995-2010)
Objective: To examine white matter hyperintensity grade (WMHG) by parkinsonism type, and the association between WMHG and mortality among incident parkinsonism patients in a population-based…Closed loop spinal cord stimulation restores locomotion and desynchronizes corticostriatal beta oscillations
Objective: To test if closed loop Spinal Cord Stimulation (SCS) could be used to restore locomotion in a 6-hydroxydopamine (6-OHDA ) rodent model of Parkinson's…
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