A post-mortem and in vivo study of neuroinflammation and Toll like-receptors in Parkinson’s disease
Objective: To investigate inflammatory change and Toll-like receptor (TLR) expression in human post-mortem Parkinson’s disease (PD) brains and to test the efficacy of TLR-blocking agents…Natural occurring antibodies reduce aggregation of α-synuclein
Objective: We tested naturally occurring antibodies (nAbs) against α-synuclein both in vitro as well as in HEK293T cells to determine binding, cell viability and capacity…Patients with Parkinson’s disease and psychosis have altered structural connectivity of the executive and visual networks
Objective: To analyze the integrity of visual and executive network of patients with Parkinson’s disease (PD) with psychosis (PD-P) and those without psychosis (PD-NP) and…Identifying delirium and it prevalence in idiopathic Parkinson’s disease
Objective: To determine diagnostic criteria used to identify delirium in Parkinson’s disease (PD) and its prevalence via a systematic literature review. Background: People with PD…Preliminary Results of Psychometric Properties of the Freezing of Gait Questionnaire in Turkish Patients with Parkinson’s Disease
Objective: To investigate the validity and reliability of the Freezing of Gait Questionnaire (FOG-Q) in Turkish Parkinson’s disease (PD) patients. Background: Freezing of gait is…Item Response Theory Analysis of the Unified Dyskinesia Rating Scale Items
Objective: To investigate the measurement characteristics of the Unified Dyskinesia Rating Scale (UDysRS) using item response theory (IRT) approaches. Background: The UDysRS has become the…Bipolar directional DBS in VIM-stimulated patients
Objective: To compare circular, directional and bipolar stimulation in VIM-implanted PD- and ET-patients regarding effect and side-effect thresholds in a cross-sectional design. Background: So far,…Therapeutic exposures of CX-8998, a potent, selective and state dependent Cav3 channel antagonist in development for Essential Tremor and Parkinson’s disease Tremor in Cav3 driven neurological models
Objective: In this study, we utilized preclinical data to establish predicted human therapeutic exposures of the potent, selective and state-dependent Cav3 channel antagonist, CX-8998, currently…The Research of the Structural Changes of Cerebellar Tissue in Tremor-type Parkinson’s Disease Based on DKI
Objective: Using Diffusion Kurtosis Imaging (DKI) to observe the structural changes of the cerebellum in patients with tremor-type Parkinson’s Disease (PD), and to provide a…An open labeled, observational study for the Satisfaction and Preference of the Rivastigmine patch for treatment of Alzheimer’s disease and Parkinson’s disease dementia (SAFE-ADPD) in Koreans
Objective: This study performed to access caregiver’s satisfaction and preference of the Rivastigmine patch for treatment of Alzheimer’s disease and Parkinson’s disease dementia patients to…
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