A53T mutant human α-synuclein BAC transgenic mice as a model for Parkinson’s disease
Objective: The aim of this study is to create mouse models reproducing the course of PD pathology and symptoms. Background: Parkinson's disease (PD) is a…Evidence based management of Normal Pressure Hydrocephalus: Lessons and future directions
Objective: To present the methodology and management tree of patients referred to the Henry Ford NPH conference for an evaluation from 2003 to 2017. Background:…Cerebellar signs in progressive supranuclear palsy
Objective: To present a patient with cerebellar ataxia and a pathologically confirmed diagnosis of PSP. Background: Progressive supranuclear palsy (PSP) is an atypical form of…MSA Preliminary Panamerican Report
Objective: To report the results of the PAN American MSA (PANMSA) database Background: Multiple system atrophy (MSA) is a rare neurodegenerative disease and coordinated efforts…Serum insulin-like growth factor-1 levels in parkinsonism or dementia disorders
Objective: To investigate serum insulin growth factor-1 (IGF-1) levels in neurodegenerative disease and to correlate clinical parameters. Background: IGF-1 is highly expressed in the central…Rapamycin for treating MSA: A preclinical proof of concept study
Objective: To assess the effects of rapamycin on motor behavior, α-synuclein burden and surrogate markers of neurodegeneration in a transgenic mouse model of multiple system…Assessment of CSF biomarkers clinical value in Progressive Supranuclear Palsy
Objective: To evaluate diagnostic and prognostic usefulness of a panel of CSF biomarkers in PSP patients presenting with Richardson’s Syndrome (RS). Background: PSP is a…Finger Tapping Profile in “On State” PD Patients
Objective: We intent to explore the tapping profile in PD patients in "ON state" compared to controls in repetitive trials to clarify if motor control…Physical activity in people with Parkinson’s disease: A qualitative study
Objective: This study aimed to investigate how Australians with Parkinson’s disease (PD) perceive participation in physical activity, and to identify barriers and enablers. Background: Exercise…Annual Clinical Evaluation in Out Patient Clinic May Improve Quality of Life in Patients with Parkinson’s Disease
Objective: The aim of this study was to examine whether the annual clinical evaluation system improves QOL in Parkinson’s disease (PD) patients. Background: We perform…
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