A Study of Pain in Parkinson’s Disease
Objective: To study the prevalence, type and severity of pain in patients with Parkinson’s disease. Background: Pain is one of the recognised non-motor symptoms in…New evidence for thalamic dysfunction in Parkinsonian rats
Objective: Abnormal oscillatory activity within the cortico-basal ganglia (BG)-thalamo-cortical circuit has been observed in Parkinsonian state, especially of β and γ bands (βB and γB).…The difference in posture reaction against backward perturbation between patients with Parkinson’s disease and healthy controls
Objective: To investigate the posture reaction in patients with Parkinson’s disease (PD) and healthy age-matched controls when they were given quantitative backward perturbation. Background: Although…Tetrahydroisoquinoline Molecule Identified in Traditional Ayurveda Medicine Modulates Inflammation in MPTP Mice
Objective: Potential ‘Anti-parkinsonian’ activity of a tetrahydroisoquinoline (TIQ) molecule of traditional ‘Ayurveda’ medicine was tested in a preclinical MPTP mice model for Parkinson’s disease (PD).…Activation of chaperone-mediated autophagy reduces oligomeric alpha-synuclein accumulation in LRRK2(R1441G) knockin mouse model of Parkinson’s disease (PD)
Objective: To determine age-dependent accumulation of oligomeric alpha-synuclein in the brain of aged LRRK2(R1441G) knockin mice; and to explore whether activation of chaperone-mediated autophagy (CMA)…Prefrontal cortical stimulation to treat anxiety and depression in Parkinson’s disease
Objective: The aims of this study are 1) to study the neurophysiology underlying anxiety and depression in PD patients, and 2) to determine whether cortical…Direction of Turning in Parkinson’s Disease: More Affected Side or Less Affected Side?
Objective: The aim of this study is to investigate differences of gait characteristics according to direction of turning more and less affected side (MAS and…Neuropathological correlates of psychiatric disorders in PD
Objective: To test the hypothesis that neuropsychiatric symptoms (NPS) in PD are associated with histopathologically confirmed neuronal loss and gliosis (NLG) in the locus coeruleus…Impulsive-Compulsive Behaviour disorders: A longitudinal study in de-novo in Parkinson’s disease patients
Objective: To investigate whether early development of impulsive-compulsive behaviours (ICB) in de novo Parkinson’s disease (PD) is associated to a different clinical progression of motor…Patterns of Long-Term Custodial Care in Parkinson Disease Psychosis
Objective: Parkinson Disease (PD) progression is frequently associated with development of psychosis (P), leading to significant morbidity, caregiver distress, and other consequences. Although PDP often…
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