Dual hit model of Parkinson’s disease propagation using MRI biomarkers and partial least squares path modeling
Objective: This study aimed using multimodal MRI to test two models of Parkinson’s disease propagation and investigated how the models were influenced by the presence…Functional connectivity of brain autonomic centers reveals associations with cardiovascular autonomic dysfunction in Parkinson’s disease
Objective: To investigate differences in functional connectivity of key autonomic brain structures that distinguish those with orthostatic hypotension (OH) from those without among subjects with…Normative vs. patient-specific brain connectivity in Deep Brain Stimulation
Objective: The objective of this study was to compare similarities and differences between patient-specific, disease-matched and normative structural connectivity seeding from deep brain stimulation (DBS)…Clinical and oculomotor correlates with freezing of gait in Chinese Parkinson’s disease
Objective: to investigate the clinical and oculomotor associations with freezing of gait (FOG) in Chinese Parkinson’s disease (PD). Background: FOG in PD has been reported…Adaptive vs Conventional deep brain stimulation for Parkinson’s disease: a eight-hours study
Objective: To compare the clinical efficacy of unilateral conventional DBS (cDBS) vs adaptive DBS (aDBS) based on local field potentials (LFP) delivered for 8 hours…Reduced Striatal VMAT2 in REM Sleep Behavior Disorder: A Gateway to Preclinical Parkinson’s Disease
Objective: To determine the degree of striatal degeneration that occurs in subjects with REM Sleep Behavior Disorder (RBD) and assess whether this is an appropriate…Is probable REM sleep behavior disorder a risk factor of impulsive-compulsive behaviors in Parkinson’s disease? PPMI study
Objective: To assess the association of REM sleep behavior disorder (RBD) with the development of impulse compulsive behaviors (ICBs) in patients with early Parkinson’s disease (PD)…Non-Motor Fluctuations in Parkinson’s Disease (PD): Development and Validation of the Non-Motor Fluctuation Assessment Instrument (NoMoFA)
Objective: Validate and demonstrate reliability of the NoMoFA. Background: In patients with PD, sleep, mood, cognitive, autonomic and other non-motor symptoms (NMS) may fluctuate (NMF)…Pet ownership associated with lower apathy and motor severity in female participants with PD
Objective: This study evaluated the impact of pet ownership on Parkinson’s disease (PD) severity and related symptoms. Background: PD is a common neurodegenerative disease characterized…Profile of non motor symptoms in familial Parkinson’s disease
Objective: Non motor symptoms have a significant contribution to the quality of life of patients with Parkinson’s disease.The aim of the study was to assess the…
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