Targeting the Receptor of Glial Cell Line-Derived Neurotrophic factor to treat Parkinson’s Disease
Objective: Our goal is to develop small molecules which support and restore nigrostriatal dopamine neurons by activation of glial cell line-derived-neurotrophic factor (GDNF) receptors. Background:…Secondary Vascular Parkinsonism: Role of increasing levels cortisol in the cognitive impairment
Objective: Elevated cortisol levels are found in many diseases, including infectious, related to aging, depression, and associated with a depressive status. Elevated cortisol levels are…Atypical Psychogenic Nonepileptic Seizure (PNES) preceding Multiple System Atrophy (MSA)
Objective: To share a case report of Atypical PNES and MSA. Background: Multiple system atrophy (MSA) is a rare neurodegenerative diagnosis that clinically presents with…MRI evaluation of Progressive Supranuclear Palsy
Objective: We aimed to evaluate the magnetic resonance imaging-derived parameters in differentiation of patients with progressive supranuclear palsy from patients with Parkinson’s disease and other…Use of Figurative Language in Describing OFF Periods in Parkinson’s Disease
Objective: To explore the use of figurative language by individuals with Parkinson’s disease (PD) describing their experience during OFF periods. Background: OFF periods are characterized…Socio-economic determinants of diagnostic latency in Parkinson’s disease patients
Objective: Early diagnosis is important in optimal management of patients with Parkinson’s disease (PD). There are several factors which can contribute to delay in diagnosis,…Diverse Phenotypic Variations Among Siblings with NBIA: A Case Report and Review of Literature
Objective: The purpose of this case report and literature review is to increase the awareness of practicing clinicians regarding the mosaic clinical pattern this disease…Functional Movement Disorder in Young Athletes: A Retrospective Case Series
Objective: To present six young athletes with functional movement disorder (FMD) engaged in competitive high school or college sports. Background: FMD is defined by involuntary…Higher exercise self-efficacy is a predictor of clinically meaningful walking activity change in people with Parkinson disease
Objective: To determine which factors at baseline predict responsiveness to a 12 month physical activity intervention in people with Parkinson’s disease (PD). Background: Previous studies…Cognitive and psychiatric symptoms are associated with walking difficulties in mild Parkinson’s disease
Objective: To investigate the association of different aspects of cognitive impairment, depression and anxiety with walking difficulties in daily life in persons with mild PD.…
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