MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Safety of MRI performed with leads-only or fully implanted DBS system

    J. Wilden, C. Torres Diaz, S. Groppa, D. Gaudin, E. Hargreaves, D. Vansickle, P. Slotty, A. Gharabaghi, E. Jiltsova, S. Ojemann, J. Aldred, S. Redding, D. Weiss, F. Defresne, E. Karst, B. Cheeran, R. Gross (Shrevport, USA)

    Objective: To support the safety of the Infinity DBS system with MR Conditional labeling. Background: An international, multicenter, observational, prospective, single-arm, post-market clinical follow-up study…
  • MDS Virtual Congress 2021

    Evaluating Patients’ Preferences for Parkinson’s Disease Treatments

    M. Serbin, J. Sutphin, C. Leach, C. Mansfield, C. Yonan, O. Klepitskaya, M. Sheehan, A. Donnelly (San Diego, USA)

    Objective: To identify patients’ preferences for attributes of oral medications that are added to levodopa or levodopa/carbidopa (LD/CD) regimens to reduce OFF-time for Parkinson’s disease…
  • MDS Virtual Congress 2021

    Patient and Care Partner Perspectives on a Community-Based Outpatient Palliative Care Intervention for Parkinson’s Disease and Related Disorders‬

    M. Bock, R. Ayele, Z. Macchi, M. Dini, M. Katz, B. Kluger (San Francisco, USA)

    Objective: To understand patient and care partner perspectives on a community-based outpatient palliative care intervention for patients with Parkinson’s disease and related disorders (PDRD). Background:…
  • MDS Virtual Congress 2021

    A Milestone-based approach to monitoring disease progression in Parkinson’s disease

    M. Brumm, A. Siderowf, T. Simuni, C. Caspell-Garcia, L. Chahine, T. Foroud, V. Arnedo, A. Reimer, C. Tanner, K. Poston, D. Weintraub, S. Hutten, K. Kieburtz, K. Marek, C. Coffey (Iowa City, USA)

    Objective: We used Parkinson Progression Marker Initiative (PPMI) data to assess the frequency of clinically meaningful disease milestones and examine baseline predictors of reaching these…
  • MDS Virtual Congress 2021

    The ADOPTION (eArly levoDopa with Opicapone in Parkinson’s paTients wIth motOr fluctuatioNs) study in Parkinson’s disease: design and rationale of a randomized prospective, open-label exploratory trial

    J. Ferreira, W. Poewe, O. Rascol, F. Stocchi, A. Antonini, R. Costa, D. Magalhães, J. Rocha, P. Soares-da-Silva (Lisbon, Portugal)

    Objective: This study aims to explore the potential of opicapone (OPC) to optimize levodopa (L-dopa)/dopa decarboxylase inhibitor (DDCi) as first-line approach to treat wearing-off in…
  • MDS Virtual Congress 2021

    Re-thinking enrollment of Deep Brain Stimulation patients in Parkinson’s Disease Clinical Trials

    J. Jimenez-Shahed, J. Rosenow, S. Miocinovic, L. Luo, C. Aquino, D. Corcos, P. Agarwal (New York, USA)

    Objective: To report on a survey of Parkinson’s disease (PD) experts on the inclusion of PD patients with deep brain stimulation (DBS) in clinical trials.…
  • MDS Virtual Congress 2021

    The Role of the PD Diary Trainer/Reviewer in Parkinson’s Disease Clinical Trials

    C. Mañeru, S. Meyer (Barcelona, Spain)

    Objective: To examine the experience profile of PD Diary raters in clinical trials Background: The Parkinson’s Disease (PD) Home Diary (Hauser, 2000)1 is a widely…
  • MDS Virtual Congress 2021

    Therapy to Reduce dementia risk In Parkinson’s disease (TRIP): Proof-of-concept trial

    D. Pourzinal, A. Bakker, G. Byrne, K. Mcmahon, J. O'Sullivan, R. Adam, A. Lehn, D. Copland, J. Yang, G. Pontone, T. Au, R. Littleford, M. Chatfield, Z. Mari, N. Dissanayaka (Herston, Australia)

    Objective: The TRIP proof-of-concept study examines functioning of the hippocampal DG/CA3 subregion as a biomarker and therapeutic target for memory impairment in Parkinson’s Disease (PD).…
  • MDS Virtual Congress 2021

    Impact of specialized light therapy in Parkinson’s disease on MDS-UPDRS parts 1-3 subscales

    B. Wyman, S. Hendrix, S. Hennessey, S. Dickson, J. Groves, W. Croft, D. Adams (Draper, USA)

    Objective: An exploratory analysis to examine the MDS-UPDRS 1-3 subitems of PD patients who underwent specialized light therapy (SLT) to assess the breadth of impact…
  • MDS Virtual Congress 2021

    Effect of oxytocin on response inhibition in Parkinson´s disease: a pilot study

    F. Carbone, P. Ellmerer, S. Spielberger, M. Peball, V. Sidoroff, M. Ritter, K. Seppi, W. Poewe, A. Djamshidian (Innsbruck, Austria)

    Objective: To observe the effect of oxytocin (OXT) on response inhibition in Parkinson´s disease (PD) patients using dedicated saccadic tasks. Background: Cumulating evidence has shown…
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