PLA2G6-related dystonia-parkinsonism in identical twins manifesting at an advanced age: a case report and review of the literature.
Objective: To report a rare presentation of a rare disease and illustrate the range of phenotype seen in PLA2G6-associated dystonia-parkinsonism (PLADP). Background: PLA2G6 encodes a…Effectiveness of a home-based exercise program on gait characteristics in an individual with Parkinson’s disease over a one-year period: A case study
Objective: The purpose of this study was to explore the case history of an individual with Parkinson’s disease (PD) who used a home-based exercise programme…Isolated ZIC4 antibody associated paraneoplastic cerebellar degeneration
Objective: Anti-ZIC4 antibodies have recently been associated with paraneoplastic cerebellar degeneration (PCD) and are usually associated with small cell carcinoma lung. However, most of the…Machine learning-based classification of SCA1, SCA2, and Healthy controls using graph features
Objective: To differentiate genetic variants of spinocerebellar ataxia (SCA1 and SCA2) and healthy controls using machine learning on resting-state functional Magnetic Resonance Imaging graph features.…Plasma p-Tau181 and p-Tau231 in Parkinson’s Disease
Objective: To explore whether plasma phosphorylated tau (p-Tau) 181 and p-Tau231 levels are associated with cognition in a Parkinson’s Disease (PD) cohort. Background: We recently…Diffusion-weighted imaging based free-water investigation in Parkinsonian disorders
Objective: To investigate free-water (FW) changes in Parkinson's disease (PD), Multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Background: Various parkinsonian syndrome includes PD,…Unilateral Hypertrophic Olivary Degeneration in Anti-GAD-associated Encephalomyelitis
Objective: We present a patient with GAD65-Ab-related encephalomyelitis who developed unilateral hypertrophic olivary degeneration (HOD) in the absence of structural lesions within the Guillain-Mollaret triangle.…Computer vision can detect changes in bradykinesia associated with dopaminergic state in Parkinson’s disease
Objective: To evaluate the classification accuracy of a computer vision-based feature extraction and classifier method to detect changes in finger tap bradykinesia associated with dopaminergic…Efficacy of Apomorphine Sublingual Film Versus Subcutaneous Apomorphine for the Treatment of OFF Episodes in Parkinson’s Disease
Objective: Evaluate efficacy and patient satisfaction associated with apomorphine sublingual film (SL-APO) vs subcutaneous apomorphine (SC-APO) for the treatment of OFF episodes in patients with…Longitudinal Assessessment of Social Cognition in de novo PD patients and its Relationship with Striatal Dopaminergic Innervation
Objective: To prospectively assess social cognition (SC) in newly diagnosed, cognitively normal Parkinson’s disease (PD) patients and its relationship with striatal dopaminergic innervation. Background: SC…
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