Long-Term Neuropsychological Outcomes of Deep Brain Stimulation in Early-Stage Parkinson’s Disease
Objective: To report long-term (5-year and 11-year) neuropsychological outcomes from the deep brain stimulation (DBS) in early-stage Parkinson’s disease (PD) pilot clinical trial. Background: The…Updated Parkinson’s disease motor subtypes classification and correlation to CSF HVA and 5-HIAA levels
Objective: To update a motor subtypes classification using the MDS-UPDRS and determine if CSF neurotransmitter profiles (HVA and 5-HIAA) are different between MDS-UPDRS subtypes in…Functional MRI and gait analysis characteristics in patients with idiopathic rem sleep behavior disorder
Objective: The aims of this study were to assess gait analysis, neurological, neuropsychological and resting-state functional MRI (RS-fMRI) functional connectivity (FC) characteristics in iRBD patients…Longitudinal clinical and biomarkers characteristics of non-manifest LRRK2 G2019S carriers: The PPMI cohort
Objective: To examine 2-year longitudinal change in clinical, dopamine transporter (DAT) imaging and biofluid biomarkers in non-manifesting carriers (NMCs) of LRRK2 G2019S versus healthy controls…Longitudinal study of Parkinson’s disease-related pattern with resting state functional MRI
Objective: To validate the previously characterized resting-state fMRI (rs-fMRI) Parkinson’s disease (PD)-related pattern, termed fPDRP, in a large multi-site PD imaging database, and to assess…P2B001 in the management of untreated PD. Results from a randomized, double-blind, double-dummy controlled trial
Objective: Evaluate the efficacy and safety of P2B001 compared with its components and with Extended-Release pramipexole (ER-PPX, calibration arm) in untreated PD. Background: P2B001 is…Postural Instability in Parkinson’s Disease: Phenotypic data from The Cincinnati Cohort Biomarker Program
Objective: To estimate the onset of postural instability in a cohort of Parkinson's disease (PD) patients. Background: The Cincinnati Cohort Biomarker Program (CCBP), launched in…Caregiving patients with Parkinson disease treated with deep brain stimulation: a systematic review and meta-synthesis of qualitative research
Objective: To explore the experiences and unmet needs of Parkinson disease patients (PDPs) caregivers after subthalamic nucleus deep brain stimulation (STN-DBS) by performing a systematic…Marker Progression and Sample Sizes Estimates for Trials in Prodromal Parkinson’s Disease: A Multicenter Study
Objective: To inform the design of randomized neuroprotective trials in prodromal Parkinson’s disease (PD) by assessing the progression of prodromal markers in idiopathic rapid eye…Association between dihydropyridines and dementia conversion in Parkinson’s disease
Objective: To investigate the role of antihypertensive drugs, including dihydropyridines, on nigrostriatal dopamine and dementia conversion in Parkinson's disease Background: Several experimental and clinical studies…
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