SCFAs participate in the pathogenesis of Parkinson’s disease by regulating NLRP3 inflammasomes activation
Objective: To explore the role and related mechanism of gut microbiota metabolites short-chain fatty acids(SCFAs) in the pathogenesis of Parkinson's disease(PD). Background: Growing research have…Gait abnormalities relate to increased extracellular water in the substantia nigra in Parkinson’s disease patients
Objective: The aim of this study was to investigate the role of substantia nigra microstructural integrity in parkinsonian gait impairments. Background: Gait impairments are common…Nicotine and influences on hyperkinetic movement disorders
Objective: We describe hyperkinetic movement disorders with a variable response to smoking and nicotine and review clinical and pre-clinical evidence regarding the role of smoking,…The Hidden Disease Burden and Treatment Experience of Patients with Essential Tremor: A Retrospective US Claims Analysis
Objective: To describe the attributes of patients with essential tremor (ET), associated comorbidities, and ET treatments using a US claims database. Background: ET is estimated…Balance evaluation in Parkinson’s disease using a set of simple tests
Objective: The study aimed to evaluate balance using a proposed set of tests in people with Parkinson’s disease compared to healthy people. Background: Numerous balance…Impulse control disorder following bilateral pallidothalamic tract focused ultrasound: a case report
Objective: Description of a case of ICD following non-contemporaneous bilateral pallidothalamic focused ultrasound tractotomy. Background: Impulsive and compulsive behaviours in PD are hypothesized to largely…Compound heterozygous PANK2 variants in two unrelated kindreds with atypical PKAN
Objective: To describe two unrelated individuals with progressive, late-onset Pantothenate kinase-associated neurodegeneration (PKAN) and a common missense variant in the PANK2 gene Background: Neurodegeneration with Brain-Iron Accumulation…Changes in gait and mobility measures collected in daily living conditions, in different stages of Parkinson’s disease
Objective: To explore mobility measures collected in daily-living conditions in different stages of PD. Background: Gait and mobility impairments are considered a cardinal sign in…Clinicopathologic features of primary lateral sclerosis with TDP-43 presenting as atypical parkinsonism
Objective: To clarify clinicopathologic features of pathologically-confirmed primary lateral sclerosis (PLS). Background: PLS is a neurodegenerative disorder characterized by slowly progressive upper motor neuron signs…Non-motor symptom characteristics in patients with essential tremor
Objective: The objective of this study was to evaluate non-motor symptoms in essential tremor (ET) and compare those to healthy controls (HCs). Background: ET is…
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