Deep Brain Stimulation of the Subthalamic Nuclei in Advanced Parkinson’s Disease what Effects on Motor Non-motor and Neuropsychological Functions a Monocentric Prospective Study with a 12-month Follow-up
Objective: The aim of the study is to assess the evolution of motor symptoms (MS), non-motor symptoms (NMS) and neuropsychological functions (NF) in Parkinson's disease…Case Report Increasing ‘On-time’ Using Mucuna pruriens Concomitantly with Traditional Levodopa/carbidopa Management
Objective: Case study to see if concomitant use of the botanical Mucuna pruriens with traditional levodopa/carbidopa management could improve patient ‘off-time.’ Background: Mucuna pruriens is a pantropical legume…ilex Paraguariensis (Yerba mate) modulates the AMPK pathway and downstream key metabolic mechanism that may explain its neuroprotective role.
Objective: To investigate the molecular pathways regulated by yerba mate [YM] extract and its main active compounds in a neuronal cell line as a cue…Age- and Sex-Associated Changes in the Behavior of Neuronal Mitochondria During Healthy Aging
Objective: To determine age-associated changes in the size, density, movement, and dynamics of mitochondria as a function of sex, using microRNA-induced neurons derived from primary…Gut Microbiota May Alter Glucose Metabolism in Patients with Parkinson’s Disease
Objective: To compare the gut microbiota in patients with Parkinson’s disease (PD) and healthy controls and predict the functional pathways associated with these differences. Background:…Motor and Non-Motor Outcomes of Bemdaneprocel in People With Parkinson’s Disease: Results up to 24 Months From a Phase 1 Study
Objective: To describe the effects of bemdaneprocel on motor and non-motor outcomes in participants with Parkinson’s disease (PD) up to 24 months post transplantation (12…A Curious Case of Copper de-Compensation
Objective: To describe the investigation and management of a patient with Wilson’s disease who experienced late-onset neurological deterioration despite continued treatment. Background: Wilson’s disease is…Hemiparkinsonism Induction with 6-OHDA in Primates Does Not Induce SN Hyperechogenicity.
Objective: We aimed to investigate the changes in SN echogenicity in primate models of hemiparkinsonism induced by 6-OHDA. Background: Hyperechogenicity in the midbrain demonstrated by…A Kinematic and fMRI Study of the Neural Correlates of Bradykinesia in Parkinson’s Disease
Objective: This study aimed at investigating the neural and kinematic correlates of bradykinesia during hand-tapping in people with Parkinson’s disease (pwPD) relative to healthy controls.…Decrease in Walking Ability with Increased Functional Connectivity between Multiple Brain Areas in Parkinson’s Disease
Objective: To compare the functional connectivity of PFC, PMC, and PSC regions during walking between individuals with Parkinson's disease and healthy controls. Background: Gait disturbances…
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