Benzodiazepines in the Management of Restless Legs Syndrome: A Systematic Review and Meta-Analysis
Objective: To evaluate the efficacy and safety of benzodiazepines (BZD) as treatment for Restless Legs Syndrome (RLS), compared to placebo or other drugs. Background: RLS…Moderate-to-severe upper limb spasticity patterns in the elderly are improved following treatment with incobotulinumtoxinA: a pooled analysis
Objective: To compare upper limb spasticity (ULS) severity changes from baseline in different spastic patterns at 4 weeks and 12 weeks post-injection of incobotulinumtoxinA (incoA)…Disease Burden and Treatment in Patients With Essential Tremor in the United States: Real-World Evidence From a Cross-Sectional Survey of Physicians and Patients
Objective: To characterize disease burden and medication treatment insights in patients with essential tremor (ET) using Adelphi Essential Tremor Disease Specific Programme (DSP)TM data. Background:…Clinical differentiation between dystonic tremor and Parkinson’s disease based on tremor characteristics
Objective: We aimed to identify clinical characteristics that are useful for differentiating dystonic tremor (DT) and Parkinson's disease (PD). Background: DT is often challenging to…Changes In Glucose Metabolism In Essential Tremor: Within And Beyond The Cerebello-Thalamo-Cortical Circuit
Objective: To investigate differences in brain glucose metabolism between patients with essential tremor and healthy controls using [18F]FDG PET brain imaging. Background: The pathophysiological mechanisms…Writing dystonia in children improves after chronic stimulation of globus pallidus internus
Objective: To analyze clinical characteristics of writing dystonia in a pediatric cohort, and test clinical efficacy of globus pallidus internus (GPi) chronic deep brain stimulation…A Homozygous Variant in NAA60 is Associated with Primary Familial Brain Calcification
Objective: To identify novel genes in autosomal recessive Primary Familial Brain Calcifications (PFBC).To identify novel genes in autosomal recessive Primary Familial Brain Calcifications (PFBC). Background:…Association of Gaucher-related and Parkinson’s-private GBA1 variants with progression of PD: A longitudinal mixed model analysis.
Objective: To compare progression of motor- and non-motor symptoms in people with Parkinson’s disease (PD) with Gaucher-related gene glucocerebrosidase (GBA1) variants compared to people with…Association between Genetic Polymorphisms and Disease Progression in Parkinson’s disease
Objective: In this study, we aim to elucidate the association between the various haplotypes of the Catechol-O-methyltransferase (COMT) and Monoamine oxidase B (MAO-B) genes, the…Strategic Training Framework for Advancing Research Capacity through GP2
Objective: To promote and facilitate learning by providing resources and expertise to address the training needs of the Global Parkinson’s Genetics Program (GP2; www.gp2.org) and…
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