Expanding the Scope Beyond Neurosurgery: A Systematic Review on MRgFUS Complications
Objective: This systematic review aims to investigate the complications associated with MRgFUS (magnetic resonance-guided high intensity focused ultrasound) for neurological disorders and determine their frequency…Role of presenilin 1 variants in parkinsonism
Objective: To characterize presenilin 1 gene (PSEN1) variants which can cause parkinsonism. Background: Variants in PSEN1 are associated with early onset Alzheimer’s disease mainly due…Heterozygous ATP7B variants in patients with parkinsonism
Objective: To describe a retrospective case series of thirteen cases carriers of heterozygous variants of the ATP7B gene manifesting with specific cases of parkinsonism. Background:…LRRK2 Mutation in a Patient with NMDA and GAD 65 Antibodies
Objective: To describe case of a patient who presented with a history of autoimmune encephalitis with NMDA receptor and GAD 65 antibodies positive in cerebrospinal…Alterations in Basal Ganglia Synaptic Density and Thalamic Gray Matter Volume are associated with Motor Signs in Late Life Depression: an 11C-UCB-J PET/MR study.
Objective: To investigate differences in the association of motor signs with synaptic density, gray matter volume and white matter lesion volume in patients with late…Changes in Inhibitory Control Differentiate Progressive Supranuclear Palsy from Early Parkinson’s Disease
Objective: To describe distinct type of errors and frequency of perseverative errors in executive, memory, language, and attentional tasks in PSP and PD. Background: Progressive…Rethinking Parkinsonism: Limitations in Clinical Diagnosis
Objective: To highlight the limitations in clinically differentiating PD and MSA. Background: The antemortem differentiation of parkinsonian syndromes remains challenging due to overlapping symptomatology, particularly…Plasma Neurofilament Light Chain and Orthostatic Hypotension in Isolated REM Sleep Behavior Disorder: A Biomarker for α-Synucleinopathy Progression
Objective: This study aims to assess plasma NfL levels in iRBD and their utility in detecting early neurodegenerative changes. Background: Rapid-Eye-Movement (REM) sleep behavior disorder…White Matter Abnormalities in Progressive Supranuclear Palsy (PSP) vs. Parkinson’s Disease (PD): Evaluation with a Convolutional Neural Network (CNN)-Based Tool
Objective: This study aimed to compare white matter hyperintensity (WMH) burden between PSP and PD using a novel AI-based tool for more accurate WMH volume…LED Light as an Inductor of Optogenetic Activation of Astrocytes in Multiple System Atrophy
Objective: The pathogenesis of Multiple System Atrophy (MSA) involves the spread of misfolded α-synuclein from nerve cells to glia and dysfunction of mitochondria and proteasomes,…
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