Evaluating the Efficacy of Virtual Reality Simulations in Enhancing Balance Recovery Among Older Adults: A Systematic Review Using Statistical Modeling
Objective: To systematically evaluate the effectiveness of virtual reality (VR) simulations in enhancing balance recovery among older adults through statistical modeling. Background: Age-related declines in…Unsupervised Analysis and Clustering of 3D Parkinsonian Gait
Objective: To investigate whether deep neural networks can learn meaningful representations of gait in Parkinson’s disease (PD), and to probe whether these representations group PD…Electrochemical Sensing for Accurate L-Dopa Detection in Parkinson’s disease
Objective: This study aims to develop a cost-effective, portable electrochemical sensor for real-time L-dopa monitoring in PD patients, addressing the limitations of current detection techniques.…Ecologically Valid, Ambient, Longitudinal, and Unbiased Assessment of Treatment Efficacy in Parkinson’s Disease (EVALUATE-PD)
Objective: To determine the feasibility of using in-home digital biomarkers (DBs) and activity monitoring for clinical trials and studies of early Parkinson’s Disease (PD) and…Usability Evaluation of a Web-based Interface for Self-Management, Remote Monitoring and Timely Review for Parkinson’s Disease (SMaRT-PD)
Objective: To evaluate the usability and acceptability of a user-interface for a clinical decision support system (CDSS), SMaRT-PD, for Parkinson’s disease. Background: PD is an…A Case of Autosomal Dominant Hypocalcemia Presenting with Parkinsonism and Widespread Brain Calcifications
Objective: To describe a case of CASR mutation-related hypocalcemia presenting with progressive movement disorder, cognitive decline, and widespread brain calcifications, illustrating the overlap between metabolic and neurodegenerative disorders.…Advancing LBD Diagnosis: EEG Biomarkers for Cognitive Fluctuations
Objective: The objective of the study was to identify EEG features associated with cognitive fluctuations in patients with Lewy body dementia (LBD). Background: Cognitive fluctuations…Clinical and Pathological Features of CSF1R-Related Disorder Associated with the c.2330G>A, p.R777Q Pathogenic Variant
Objective: To report the clinical and pathological features of CSF1R-RD associated with the c.2330G>A, p.R777Q variant, and to report a new family carrying this variant.…Analysis of Diagnostic Outcomes and Imaging Features in Patients with Ventriculomegaly and Gait Impairment
Objective: To describe the clinical features, diagnostic outcomes, and brain MRI imaging characteristics in patients with ventriculomegaly and gait impairment Background: Emerging evidence suggests that ventriculomegaly,…30-year Delayed Diagnosis of Juvenile Parkinson’s Disease in a Patient Misdiagnosed with Dopa-responsive Dystonia
Objective: To report a case of Juvenile Parkinson’s Disease (JP) misdiagnosed as dopa-responsive dystonia (DRD) and to emphasize the importance of early genetic testing in…
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