Decreased DTI-ALPS Indices and their Association with Clinical Features in Parkinson’s Disease
Objective: To investigate possible glymphatic dysfunction using diffusion tensor image along the perivascular space (DTI-ALPS) in patients with Parkinson’s disease and their relationship with clinical…Subthalamic nucleus DBS outcomes correlate with white matter tractography in Parkinson’s Disease
Objective: To assess whether advanced diffusion magnetic resonance imaging (dMRI) techniques help to understand the outcome of Deep brain stimulation (DBS) surgery on Unified Parkinson’s…Scans Without Evidence of Dopamine Deficiency (SWEDD) in Early-Onset Parkinson’s Disease: Comprehensive Clinical Analysis
Objective: Aim of this study is to comprehensively compare motor and non-motor symptoms of individuals with Early Onset Parkinson's Disease (EOPD) with dopamine deficiency to…Genetic Correlations Between Parkinson’s Disease and Circulating Metabolites
Objective: To use genome-wide association studies (GWASs) to identify genetic correlations between Parkinson’s disease (PD) and circulating metabolites. Background: Metabolomics is the study of small…Returning Secondary Health Findings in the PD GENEration study
Objective: To provide secondary health findings (SHF) results to participants enrolled in the PD GENEration study via CLIA genetic testing using whole genome sequencing (WGS)…A unique genetic duality: GAK and SCN4A Mutations in Myasthenic Syndrome and Early-Onset Parkinsonism in a Peruvian woman: A Case Report
Objective: To present the first genetically characterized non-linear summative damage characterized case resulting in early-onset parkinsonism associated with congenital myasthenia Background: The GAK (Cyclin G…Monogenic Parkinson’s Disease patients in Central Europe within the CEGEMOD consortium
Objective: To report the genetic results of genotyping and whole-exome sequencing (WES) data of patients with Parkinson’s disease (PD) from the Central European countries of…Genetic risk modifiers for GBA1 carriers in Parkinson’s disease: from the Global Parkinson’s Genetics Program
Objective: To identify potential genetic risk modifiers for GBA1 variant carriers across genetically determined European ancestries (European, Ashkenazi Jewish, Finnish, and Icelandic) using data from…Histopathology of long-term implants of peripheral nerve tissue into the substantia nigra of patients with Parkinson’s disease
Objective: To characterize autologous peripheral nerve tissue (PNT) implants into the substantia nigra of individuals with PD who participated in our previous clinical trials. Background:…Motor Outcomes Following Subthalamic Nucleus or Globus Pallidus Interna Deep Brain Stimulation in Early-Onset Parkinson’s Disease
Objective: Comparative outcomes between deep brain stimulation (DBS) targets in Early-onset Parkinson’s Disease (EOPD) patients are lacking. This study leverages the University of Florida’s (UF)…
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