Prevalence and Local Ancestry of LRRK2 p.Q1111H in Latin American Cohort
Objective: To expand upon previous work assessing the prevalence of the LRRK2 p.Q1111H variant in Latin America and implement local ancestry analysis to assess ancestral…Genetics of African Americans – Louisiana, Parkinson’s Disease – (GoAAL-PD)
Objective: Study a cohort of African American patients with PD to understand the genetic underpinnings, phenotypes, barriers to care, and engagement preferences unique to this…Clinical Differences Among Parkinson’s Disease Patients Carrying GBA1 Variants in Colombia: Insights From LARGE-PD Consortium
Objective: To compare the clinical manifestations of GBA1 variants p.K198E, p.E326K, and p.N370S in Parkinson’s disease(PD) patients in Colombia. Background: GBA1 variants have been identified…Assessing Individual Risk Through Determination of Local Ancestry: Insights from the Global Parkinson’s Genetics Program
Objective: We're developing a scalable pipeline to infer local ancestry (LA) for individuals in the Global Parkinson's Genetics Program (GP2). This approach aims to enhance…Screening for GBA1 p.K198E PD-Risk Variant in Latin America
Objective: We aimed to assess the distribution of the GBA1 p.K198E variant, linked to Gaucher’s disease (GD) and increased Parkinson’s disease (PD) risk, across Latin…Delirium following deep brain stimulation: An 8 year single-centre study
Objective: To describe the outcomes of patients undergoing deep brain stimulation (DBS) surgery for movement disorders and neuropsychiatric indications and characterise delirium symptoms. Background: Deep…Beyond UPDRS: personalizing the assessment of different DBS modes
Objective: The added benefit from adaptive (aDBS) compared with conventional deep brain stimulation (cDBS) is largely heterogeneous, and the perceived benefit is subjective. In this…Deep Brain Stimulation in Late-Stage Parkinson’s Disease: Insights from Clinical Practice
Objective: To compare Late-stage Parkinson's disease (LSPD) patients who completed at least one year of oral medical therapy alone after IPG depletion with those who…Rescue GPi DBS for Severe Dyskinesias and Dystonia in Long-Term STN DBS Parkinson’s Patients: A Case Series
Objective: Evaluate GPi DBS as a rescue therapy for refractory dyskinesias and dystonia in long-term STN DBS patients. Background: STN DBS effectively reduces medication dependency…Olfactory-Trigeminal Interactions in Parkinson’s Disease Compared to Other Olfactory Disorders
Objective: To investigate the interaction between the olfactory and trigeminal systems in Parkinson’s disease (PD) as opposed to other forms of olfactory dysfunction and controls…
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