MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    Detection of α-synuclein Seeds in Skin and CSF Samples from PPMI Participants.

    L. Concha-Marambio, Y. Ma, C. Farris, R. Johnson, S. Rosete-Gonzalez, D. Murphy, K. Merchant, S. Hutten, T. Simuni, T. Tropea, M. Frasier, J. Hamer, K. Marek, T. Foroud (San Diego, USA)

    Objective: To compare the distribution of α-synuclein seeds (syn-seeds) between skin and CSF samples from PPMI participants, including prodromal, early Parkinson’s disease (PD), and late…
  • 2025 International Congress

    A Prospective, Observational Study to Identify Biomarkers in Parkinsonian Syndromes (proATYP).

    M. Makrygianni, D. Potamianou, T. Pipikos, M. Xilouri, C. Mourmouris, A. Sarafi, L. Florentin, M. Stamelou (Athens, Greece)

    Objective: This is a prospective observational study to identify biomarkers in parkinsonian syndromes. Background: Parkinson’s disease (PD) and atypical parkinsonian syndromes namely progressive supranuclear palsy…
  • 2025 International Congress

    Classification of Medication State in Parkinson’s Disease Patients with and without Fluctuations using Facial Videos

    I. Boura, V. Skaramagkas, G. Karamanis, I. Kyprakis, D. Fotiadis, Z. Kefalopoulou, M. Tsiknakis, C. Spanaki (Heraklion, Crete, Greece)

    Objective: This study presents a unique, interpretable Dual-Stream Transformer model for classifying medication state in patients with Parkinson’s disease (PD) using facial videos. Background: Recent…
  • 2025 International Congress

    Can Wearable Inertial Sensors Accurately Reflect Parkinson’s Disease Severity? A Systematic Review and Meta-Analysis

    H. Youssef, M. Sabıroğlu, S. Abdelrahman, T. Hasanin, M. Manay, M. Gönül, S. Del Din, A. Vural (Istanbul, Turkey)

    Objective: To evaluate the ability of inertial measurement units (IMUs) in detecting the severity of motor symptoms in Parkinson’s disease (PD) by examining the relationship…
  • 2025 International Congress

    Baseline brain inflammation is associated with less cognitive progression at 24 months in subjects with de novo Parkinson’s disease

    T. Yacoubian, N. Stover, M. Dean, A. Amara, L. Ruffrage, H. Qin, E. Benveniste, Y. Fang, J. Mcconathy, Y. Zhang, R. Kennedy, A. Gerstenecker, D. Standaert (Birmingham, USA)

    Objective: To examine if brain inflammation measured by 18F-DPA-714 imaging is associated with cognitive change in subjects with early Parkinson’s disease (PD). Background: Evidence for…
  • 2025 International Congress

    The East London Parkinson Disease Project: cultural fairness of common cognitive screening tests

    A. Zirra, KC. Dey, E. Camboe, E. Bhadra, T. Haque, S. Waters, DA. Gallagher, C. Budu, B. Huxford, C. Simonet, C. Edwards, S. Ali, R. Weil, N. Mukadam, AJ. Lees, T. Boyle, MT. Perinan, CR. Marshall, AJ. Noyce (London, United Kingdom)

    Objective: The first objective of this work was to report the prevalence of Parkinson’s disease (PD) cognitive impairment in three ethnicities from the East London…
  • 2025 International Congress

    Ameliorating effect of linalool on anxiety disorders in Parkinson’s mice and related mechanisms

    F. Lou, M. Li (Shenyang, China)

    Objective: The aim of this study was to verify the ameliorating effect of linalool(LIN) on anxiety-related affective disorders and the associated receptors in a MPTP…
  • 2025 International Congress

    Gender Based Differences in Impulse Control Disorders within Parkinson’s Disease

    N. David, M. Steinberg, L. Higginbotham, R. Tripathi (Atlanta, USA)

    Objective: Analyze associations between gender, dopamine agonists, and levodopa doses in Parkinson’s Disease (PD) patients with Impulse control disorder (ICD). Background: ICDs, which include compulsive…
  • 2025 International Congress

    Parkinson disease subtype stability and eventual convergence

    H. Lessov-Schlaggar, A. Eid, T. Cash, E. Foster, B. Maiti, H. Hwang, R. Perrin, P. Kotzbauer, J. Perlmutter, M. Campbell (Saint Louis, USA)

    Objective: To determine the longitudinal stability of Parkinson disease (PD) subtype membership. Background: Previous research demonstrates distinct PD subtypes of “motor only”, “psychiatric & motor”,…
  • 2025 International Congress

    Exploratory Longitudinal Analysis of Lifestyle and Parkinson’s Disease Symptoms

    N. Meier, O. Di Martino, I. Chaturvedi (Irvine, USA)

    Objective: This study is an exploratory longitudinal analysis of lifestyle factors and Parkinson’s Disease (PD) symptoms that may inform targeted research into specific lifestyle interventions…
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