Levodopa and DBS Produce Discordant Effects on Parkinsonian Features
Objective: To compare the effect of levodopa vs deep brain stimulation on specific motor features of advanced Parkinson disease. Background: Levodopa (LD) is the gold…A Data Visualization Tool to Improve Interpretation of MDS-UPDRS Results Post-DBS
Objective: To evaluate the potential of our previously developed data visualization platform for the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) as a…Full-year Open-label Tracking of Adaptive Deep Brain Stimulation in Parkinson’s Disease in Two Patients: Considerations for Long-term Algorithm Maintenance
Objective: To assess the effects of chronic adaptive deep brain stimulation (aDBS) on motor symptoms and quality of life (QoL) and algorithm stability in two…Analgesic Effect of Cannabidiol and Tetrahydrocannabinol(THC) on Pain Sensitivity in Reserpine Model of Parkinson’s Disease
Objective: The objectives of the study were to determine the effect of THC and CBD on:1. Thermal nociceptive threshold in reserpine induced Parkinson’s disease2. Mechanical…Qigong Exercise on Nonmotor Symptoms in Parkinson’s Disease
Objective: This randomized controlled clinical trial examined the efficacy of a Qigong exercise on non-motor symptoms in people with Parkinson’s disease (PD). Background: Non-motor symptoms…Application of Respiratory-Controlled Cardiopulmonary Coupling in Early Diagnosis of Parkinson’s Disease
Objective: Studies have shown that autonomic nervous symptoms precede motor symptoms in PD, making autonomic function assessment a potential tool for early PD diagnosis. This…Prevalence of urinary problems in men and women with Parkinson’s disease. A study from the Mexican Parkinson’s Research Network.
Objective: To analyze whether there is a relationship between sex and the presence of genitourinary symptoms in patients with Parkinson’s disease and its impact on…Distribution of Chronotypes in Parkinson’s Disease and its association with Pathological Sleepiness
Objective: To study the distribution of chronotypes in Veterans with Parkinson's disease (PD); and its association with pathological sleepiness. Background: Excessive daytime sleepiness is a…Genotype and age at onset drive vermis atrophy in CACNA1A and GAA-FGF14 related ataxias
Objective: To assess cerebellar volumetry using a deep learning method in patients with non-polyglutamine CACNA1A- or GAA-FGF14-related disease. Background: Ion channel dysfunction is a recurring…Multiplex Proteomic Analysis of Lewy Body Dementia Reveals Cerebrospinal Fluid Biomarkers of Disease Pathophysiology and Progression
Objective: To evaluate the performance of a multiplexed proteomic assay in a large multi-center Lewy Body dementia (LBD) cohort. Background: LBD, which comprises Parkinson’s disease…
