Progression of Motor & Non-motor symptoms of Parkinson’s Disease with Prior History of Head Trauma
Objective: We compared the progression of motor (M) and nonmotor (NM) symptoms in subjects with Parkinson’s Disease (PD) with pre-existing head trauma (HT), with or…Differentiated approach to treatment and diagnosis of Parkinson’s disease
Objective: The anatomical and physiological characteristics of tremor in patients with Parkinson’s disease and essential tremor at the same age significantly influence diagnostic approaches, differentiation…Resolution Dependence of Machine Learning for Differential Diagnosis of Parkinsonian Eye Movements
Objective: To establish the extent to which high temporal resolution is required to differentiate between parkinsonian disease states from eye movements. Background: Previous studies have…Multimodal and Agentic Simulated AI Patients for Bridging the gap in Parkinson Disease Education
Objective: To develop an AI training platform in PD counseling that utilizes real-time NLP processing, multimodal inputs/outputs, and adaptive reinforcement learning supported by immediate feedback…Advancing Hypomimia Assessment in Parkinson’s Disease by Integrating a Continuous Monitoring Device into Clinical Practice
Objective: We aim to establish a robust, continuous method for monitoring hypomimia in Parkinson’s disease (PD), bridging the gap between sporadic clinical evaluations and real-life…Virtual Gait Lab: Assessment of Freezing of Gait in Parkinson’s Disease Using Virtual Reality
Objective: To develop and validate the effectiveness of a "Virtual Gait Lab" system using virtual reality (VR) technology for provoking and evaluating gait disturbances in…Digital Measures for Clinical Trial Endpoints in Huntington’s Disease (MEND-HD): Study Design and Status Update
Objective: To evaluate and establish the analytical validation, reliability, and meaningfulness of digital measures of gait and chorea in early Huntington’s disease (HD). Background: HD…Role of 7-Tesla MRI in assessing clinical symptoms in CSF1R-Related Disorders
Objective: To evaluate utility of 7-tesla magnetic resonance imaging (7T MRI) as a biomarker of CSR1R-Related Disorder (CSF1R-RD). Background: CSF1R-RD is a rapidly progressive neurodegenerative…Whispers of Hope Motor and Psychiatric Recovery in Fahr’s Disease with High-Frequency rTMS: A Case Report
Objective: To present a case of FD showing significant motor and psychiatric improvement following high-frequency rTMS of the DLPFC Background: Fahr’s disease (FD) is a…Diagnostic mismatches between clinical assessment, imaging and alpha-synuclein biomarkers in parkinsonian syndromes
Objective: To analyze the frequency of matching information provided by traditional clinical assessment, dopamine transporter (DaTscan), and skin biopsy results in patients with undiagnosed parkinsonian syndromes. Background:…
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