Staging Disease Progression from Prodromal to Overt Stage of Alpha-synucleinopathies
Objective: To compute a disease progression model of the prodromal to overt synucleinopathy continuum, usable at single subject level. Background: Progression milestones to stage patients…Distinct Peripheral Immune Profiles of Parkinson’s Disease and Multiple System Atrophy
Objective: We aimed to compare peripheral blood mononuclear cell (PBMC) subsets between Parkinson’s disease (PD) and multiple system atrophy (MSA) to identify disease-specific immune signatures…Color Vision In Patients With Clinical Manifestations Of Rem Sleep Behavior Disorder
Objective: To evaluate the presence of changes in color vision in patients with REM sleep behavior disorder (RBD), Parkinson's disease (PD), and controls. Background: Visual…Plasma Lipids as Potential Biomarkers for Progression of Sleep Disturbances in Parkinson’s Disease
Objective: Determine if plasma lipid levels can serve as a surrogate biomarker of future onset of RBD symptoms or nighttime sleep burden in patients with…Interpretable voice-based detection of Parkinson’s disease using language-independent graph neural networks
Objective: To develop a robust, interpretable, and language-independent tool for voice-based detection of Parkinson’s disease (PD) using graph neural networks (GNNs), demonstrating superior cross-linguistic generalization…Prevalence and Management of Depression Among Parkinson’s Patient’s in an Outpatient Clinic Setting
Objective: To evaluate the prevalence of depression among Parkinson’s Disease (PD) patients attending an outpatient clinic and review current management to improve diagnosis and treatment…The Role of Neuropsychiatric Symptoms in the Diagnosis of Early Parkinson’s Disease: a Systematic Review
Objective: This study aims to evaluate the role of neuropsychiatric symptoms in the diagnosis of Early Parkinson's Disease. Background: Neuropsychiatric symptoms (NPS) are important and…Changes in Cognitive Function with Deep Brain Stimulation in PD patients with and without Freezing of Gait
Objective: To determine if deep brain stimulation (DBS) changes cognitive function in Parkinson’s Disease (PD), and if these cognitive changes may relate to gait dysfunction…A Four-Arm Randomized Controlled Trial on the Effects of Multi-Dimensional Cognitive Intervention in Parkinson’s Disease with Mild and Subjective Cognitive Decline (REMIND)
Objective: To investigate the efficacy of online Brain and Body Rehab Training (BBRT) (Figure 1), a digital cognitive intervention, in Parkinson’s disease patients with mild…Trail Making Task in people with isolated REM sleep behaviour disorder
Objective: This study aimed to evaluate online remote executive function in individuals with isolated polysomnography (PSG)-confirmed REM sleep behaviour disorder (iRBD). Background: The Trail Making…
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