MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    Treatment with Mucuna pruriens Plus Solo Carbidopa Prescription in Patient Reluctant to Initiation of Traditional Levodopa/Carbidopa Medication

    T. Denne (Mission Viejo, USA)

    Objective: To see if treatment with Mucuna pruriens 2 capsules (15% levodopa) TID, plus solo carbidopa prescription 25mg TID in patient reluctant to traditional levodopa/carbidopa management could help…
  • 2025 International Congress

    Medication therapy in Parkinson’s disease patients: a cross-sectional study at the University Medical Center at Ho Chi Minh City, Vietnam

    T. Dang, T. Tran (HO CHI MINH, Viet Nam)

    Objective: To determine the rate of drugs prescribed to treat Parkinson's disease motor symptoms, the rate of the types of drug combinations, and the frequency…
  • 2025 International Congress

    Phosphorylated High Mobility Group Box Protein 2 (HMGB2) as a Potential Biomarker for Parkinson’s Disease

    J. Fan, J. Liu, C. Mesaros, I. Blair (Philadelphia, USA)

    Objective: We recently showed that HMGB2 is secreted during ferroptosis and as ferroptosis is involved in the etiology of PD, we have examined the possibility…
  • 2025 International Congress

    The Moroccan LRRK2 Registry: Building Resources to Investigate the Penetrance and Phenotype of LRRK2 in North Africans

    Y. Razouqi, M. Megraoui, F. Belahsen, L. Bouguenouch, B. Elmakhzen, H. Ouhabi, J. Aasfara, Y. Zaid, A. Atpu, L. Khalki, M. Rizig (Casablanca, Morocco)

    Objective: The Moroccan LRRK2 Registry aims to establish a comprehensive database integrating clinical data and biosamples to provide valuable insights into the penetrance, phenotype, and…
  • 2025 International Congress

    Epigenome-wide and gene-targeted epigenetic profile of isolated REM Sleep Behaviour Disorder: a clinico-molecular study

    L. Baldelli, C. Pirazzini, L. Sambati, F. Ravaioli, F. Di Laudo, D. Gentilini, P. Guaraldi, C. Franceschi, P. Cortelli, P. Garagnani, G. Calandra-Buonaura, MG. Bacalini, F. Provini (Bologna, Italy)

    Objective: Comprehensively characterize the epigenetic profile of isolated REM Sleep Behaviour Disorder (iRBD) using genome-wide and gene-targeted approaches, linking it to clinical measures and  phenoconversion.…
  • 2025 International Congress

    Facial Blendshape Index(FBI) for Quantification of Hypomimia on Parkinson´s Disease

    B. Koyak, T. Menzel, M. Botsch, A. Spottke, M. Reuter, U. Wüllner, NA. Aziz (Dortmund, Germany)

    Objective: To evaluate the validity of ExpressionTracker, an app generating personalized facial blendshapes, for objective quantification of hypomimia in patients with Parkinson’s disease (PD) [1].…
  • 2025 International Congress

    Plasma P-tau217 detects Alzheimer’s co-pathology and predicts cognitive decline in Parkinson’s disease

    T. Tropea, P. Aldea Stevenson, M. Flitter, D. Meehan, A. Morris, M. Lu, L. Iaccarino, E. Collins, M. Hodsdon, L. Shaw, E. Lee, D. Weintraub, A. Chen-Plotkin, M. Mintun, A. Siderowf (Philadelphia, USA)

    Objective: The objectives of this study are to compare plasma phosphorylated tau-217 (P-tau217) levels in Parkinson’s disease (PD) with versus without Alzheimer’s disease (AD) copathology…
  • 2025 International Congress

    Novel Usage of Alpha Synuclein as a Biomarker for Screening Parkinson’s disease at Komfo Anokye Teaching Hospital in Ghana

    YAW. Osei, SF. Sarfo, FAY. Yeboah Agyemang (Kumasi, Ghana)

    Objective: This study aimed to assess the use of alpha-synuclein as a biomarker for PD screening and investigate its correlation with disease severity. Background: The…
  • 2025 International Congress

    Cognitive Improvement in Parkinson’s Disease Patients After Intravenous Mesenchymal Stem Cell Infusion: Results from a Phase 2 Randomized Trial

    T. Thomas, J. Martinez-Lemus, E. Tharp, C. Green, C. Onuigbo, J. Suescun, T. Le, E. Rodarte Rascon, R. Ritter Iii, T. Ellmore, M. Schiess (Houston, USA)

    Objective: Assess the impact of treatment with intravenous (IV) allogeneic bone marrow-derived mesenchymal stem cells (allo-hMSCs) on cognition in patients with mild-moderate Parkinson’s Disease (PD).…
  • 2025 International Congress

    Modified Delphi consensus approach to develop recommendations for diagnosis, evaluation and management of cognitive disorders in Parkinson’s disease

    D. Pourzinal, D. Brooks, D. Sriram, L. Mitchell, N. Pachana, K. Shrubsole, B. Wood, J. O'Sullivan, R. Marsh, A. Lehn, J. Liddle, E. Tan, WK. Halford, N. Page, N. Dissanayaka (HERSTON, Australia)

    Objective: We aimed to develop harmonised recommendations for the diagnosis, evaluation and management of cognitive disorders in PD using a modified Delphi process. Background: Differences…
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