Epigenome-wide and gene-targeted epigenetic profile of isolated REM Sleep Behaviour Disorder: a clinico-molecular study
Objective: Comprehensively characterize the epigenetic profile of isolated REM Sleep Behaviour Disorder (iRBD) using genome-wide and gene-targeted approaches, linking it to clinical measures and phenoconversion.…Facial Blendshape Index(FBI) for Quantification of Hypomimia on Parkinson´s Disease
Objective: To evaluate the validity of ExpressionTracker, an app generating personalized facial blendshapes, for objective quantification of hypomimia in patients with Parkinson’s disease (PD) [1].…Plasma P-tau217 detects Alzheimer’s co-pathology and predicts cognitive decline in Parkinson’s disease
Objective: The objectives of this study are to compare plasma phosphorylated tau-217 (P-tau217) levels in Parkinson’s disease (PD) with versus without Alzheimer’s disease (AD) copathology…Novel Usage of Alpha Synuclein as a Biomarker for Screening Parkinson’s disease at Komfo Anokye Teaching Hospital in Ghana
Objective: This study aimed to assess the use of alpha-synuclein as a biomarker for PD screening and investigate its correlation with disease severity. Background: The…Cognitive Improvement in Parkinson’s Disease Patients After Intravenous Mesenchymal Stem Cell Infusion: Results from a Phase 2 Randomized Trial
Objective: Assess the impact of treatment with intravenous (IV) allogeneic bone marrow-derived mesenchymal stem cells (allo-hMSCs) on cognition in patients with mild-moderate Parkinson’s Disease (PD).…Modified Delphi consensus approach to develop recommendations for diagnosis, evaluation and management of cognitive disorders in Parkinson’s disease
Objective: We aimed to develop harmonised recommendations for the diagnosis, evaluation and management of cognitive disorders in PD using a modified Delphi process. Background: Differences…Telephone-Based Cognitive Screening for MCI to Dementia in Parkinson’s Disease
Objective: The aim of this study is to evaluate whether telephone-based cognitive screening could be an effective and sustainable alternative to traditional in-person neuropsychological assessment.…Longitudinal Analysis of Cognitive Changes in Parkinson’s Disease Subjects at Risk of Developing Probable REM Sleep Behavior Disorder (RBD)
Objective: To characterize the cognitive profile of Parkinson’s Disease (PD) patients that develop probable REM sleep behavior disorder (pRBD) within 8 years after PD diagnosis…Atypical Psychosis in Parkinson Disease: A Retrospective Study on 24-Hour Continuous Subcutaneous Infusion Foslevodopa/Foscarbidopa Therapy
Objective: This study aims to identify clinical predictors of continuous subcutaneous infusion (CSCI)-induced psychosis to understand its potential mechanisms and evaluate predictive measures for its…Subthalamic Deep Brain Stimulation Modulates Cognitive-Motor Integration in Parkinson’s Disease: Insights from a Dual-task fNIRS Study
Objective: To investigate the effects of STN-DBS on cognitive-motor dual-task performance in PD patients using an executive function-motor function dual-task paradigm combined with functional near-infrared…
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