A retrospective analysis of an FMD IDC: considerations that impact outcomes.
Objective: We aimed to evaluate the impact of demographics, clinical characteristics, and comorbidities on treatment follow up and outcomes in patients from an interdisciplinary FMD…Neurodegenerative Langerhans Cell Histiocytosis: A Rare Cause of Cerebellar Ataxia
Objective: To describe a rare case of progressive cerebellar ataxia due to neurodegenerative Langerhans Cell Histiocytosis (ND-LCH) and highlight diagnostic challenges with atypical imaging findings.…Physical, Mental, and Socioemotional Functional Improvement Following Valbenazine Treatment for TD: a Case Series
Objective: Describe clinical characteristics and changes in mental, socioemotional, and physical domains of individuals with tardive dyskinesia (TD) after valbenazine (VBZ) treatment. Background: Prior research…Nutrition, Motor And Non-Motor Symptoms Impact On Life’s Quality In Parkinson’s Disease In Second-Line Therapies
Objective: Analyze the nutritional status, motor and non-motor symptoms of patients with Parkinson´s disease (PD) with second-line therapies [levodopa carbidopa intestinal gel (LCIG) and deep…PARKinSOUND 2.0: The Impact of Orchestra Participation on Patients with Parkinson’s Disease
Objective: This study evaluates the impact of participation in a community orchestra on people with PD. Background: As interest in non-pharmacological therapies for Parkinson’s disease…Parkinson’s Progression Markers Initiative (PPMI): A Biomarker Engine for Therapeutic Development for PD and Related Synucleinopathies
Objective: PPMI is a longitudinal, observational study investigating clinical, imaging, genetic and biofluid biomarkers to accelerate therapeutic development for Parkinson’s disease (PD) and related synucleinopathies…Efficacy of adhering to a Ketogenic Diet in Parkinson’s Disease: a Systematic Review and Meta-Analysis
Objective: We aimed to analyse the efficacy of Ketogenic Diet (KD) in metabolic and motor characteristics of patients with Parkinson's Disease (PD). Background: Many studies…Parkinson’s Exercise Guidelines: From Outdated to Updated
Objective: To align the 2021 Parkinson’s Exercise Guidelines with current evidence and stakeholder feedback. Background: In 2021, the Parkinson’s Foundation, in partnership with the American…Longitudinal Analysis of BRAIN test in isolated REM sleep behaviour disorder with and without hyposmia.
Objective: To assess motor dysfunction in individuals with polysomnography (PSG)-confirmed isolated REM Sleep Behaviour Disorder (iRBD), self-reported RBD (sRBD), and sRBD with smell loss (hyposmia).…P2P Therapeutics Platform Trial in Stage 2B Neuronal Alpha-Synuclein Disease: Study Design and Statistical Considerations
Objective: To describe the study design and timeline of a platform interventional study in Neuronal α-Synuclein Disease (NSD). Background: The recent description of the biological…
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