Genetic Disorders Presenting With Tremor at Onset: MDSGene systematic literature review
Objective: We reviewed the Movement Disorder Society Genetic mutation database (MDSGene) to evaluate the prevalence, clinical features and evolution of genetic conditions presenting with isolated…Fluid Biomarkers and the 4R-Tauopathies
Objective: To investigate the prevalence and clinical relevance of AD co-pathology, assessed through fluid biomarkers, in patients with clinical 4R-tauopathies. Background: 4R-tauopathies are neurodegenerative diseases…Study on the Mechanism of SIRT3 Protecting Parkinson’s disease by Regulating Mitophagy
Objective: To clarify the protective effect of SIRT3 on Parkinson's disease (PD) and the molecular mechanism by which it regulates mitophagy. Background: PD involves movement…Gender Differences in Cervical Dystonia Patients
Objective: to research clinical features and their gender differences in CD patients Background: Cervical dystonia (CD) is a movement disorder of nervous system characterizes by…Clinical outcomes of deep brain stimulation for Parkinson’s disease in the Dominican Republic: results from a newly established single-center DBS program
Objective: To evaluate motor improvement after bilateral STN-DBS in patients with Parkinson’s disease in the Dominican Republic. Secondary objectives included assessing reduction in dopaminergic medication…Genome-wide Discovery of Genetic Modifiers of LRRK2 risk in Parkinson’s Disease Carriers across European Populations
Objective: To identify genetic risk modifiers for LRRK2 variant carriers of European ancestry. Background: The LRRK2 p.G2019S variant is associated with substantially elevated risk for…Regional α-Synuclein Seeding Activity in Parkinson’s disease and Multiple System Atrophy
Objective: This study aimed to profile regional α‑synuclein (α-syn) seeding activity in postmortem brains from Parkinson’s disease (PD) and multiple system atrophy (MSA) and to…Scaling Evidence-based Community Rehabilitation for Parkinson’s disease for Singapore: A Nationwide RE-AIM Implementation Study Protocol
Objective: This study aims to evaluate the nationwide scale-up of standardized Parkinson’s rehabilitation programs across Singapore’s community care sector using the RE-AIM (Reach, Effectiveness, Adoption,…Videonystagmography findings, Postural Balance, and Falls in Parkinson’s disease patients
Objective: To characterize the clinical profile related to oculomotor control, balance, motor severity, and frequency of fall in individuals with PD Background: Extraocular motility is…Non-Motor Phenotypes and Intestinal Microbiome Alterations in GBA1-Associated Parkinson’s Disease: Evidence for a Body-First Subtype
Objective: To characterize the clinical and microbial features of sporadic PD (sPD) and GBA1-associated PD (GBA1-PD), with a particular focus on Escherichia coli abundance, stratified…
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