Characteristics And Progression Of Non-Motor Symptoms In Parkinsons Disease
Objective: The aim of this study is to investigate the characteristics and the progression of different domains of NMS in PD, and to determine their…Parkinson disease psychosis: A systematic review and meta-analysis
Objective: To determine the prevalence of Parkinson disease psychosis (PDP) as a function of several putative risk factors: PD duration, age, cognitive impairment, dopaminergic or…Unravelling the neural correlates of visual cueing in Parkinson’s disease
Objective: Visual cueing can compensate for impaired automatic gait control in Parkinson's disease (PD) patients experiencing Freezing of Gait (FOG) by engaging goal-directed motor behaviour1.…Odor‑specific olfactory dysfunction in early‑onset Parkinson’s disease
Objective: To characterise olfactory dysfunction in early‑onset Parkinson’s disease (EOPD). Background: Olfactory loss is a frequent non‑motor feature of Parkinson’s disease and often precedes motor…Neuroinflammation and neurodegeneration biomarkers in Parkinson’s disease: integration of neuroimaging and fluid markers
Objective: To investigate the association between serum and cerebrospinal fluid (CSF) levels of NfL and GFAP and dopaminergic degeneration measured by 123I-ioflupane SPECT (DaTSCAN) in…Investigating the Role of Biallelic EPG5 Variants in Parkinson’s Disease
Objective: Investigate EPG5 role in PD aetiology. Background: Disruption of the lysosome-autophagy pathway is a recurrent feature in Parkinson’s disease (PD). EPG5 bi-allelic loss-of-function variants have been…Non‑Motor Outcomes after STN-FUS for Parkinson’s disease
Objective: To assess changes in non-motor symptoms(NMS) in PD after focused ultrasound subthalamotomy(STN-FUS). Background: NMS impair quality of life in PD.STN-FUS improves motor signs in PD but…Increased Pre-Alpha EEG Functional Connectivity Forecasts Future Cognitive Decline in Parkinson’s Disease
Objective: To evaluate whether resting-state EEG functional connectivity (rsEEG-FC) forecasts cognitive decline three years later in Parkinson’s disease (PD). Background: Cognitive performance and trajectories of…Multimodal Gait Analysis Using Video Pose Estimation Deep Learning and Walkway Parameters: Parkinsonism Detection and Phenotyping
Objective: To develop a multimodal framework fusing frontal-view video pose estimation frame coordinates with pressure-sensitive walkway features for parkinsonism detection, and to discover clinically meaningful…Late Diagnosed Kufor Rakeb Syndrome Presenting as Drug Induced Parkinsonism
Objective: Kufor-Rakeb syndrome (KRS) may present with a wide variety of psychiatric symptoms. This case describes the development of parkinsonism after antipsychotic treatment and the…
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